Results 31 to 40 of about 177,952 (253)

Slope Stability Classification under Seismic Conditions Using Several Tree-Based Intelligent Techniques

Applied Sciences, 2022
Slope stability analysis allows engineers to pinpoint risky areas, study trigger mechanisms for slope failures, and design slopes with optimal safety and reliability.
Panagiotis G. Asteris, Fariz Iskandar Mohd Rizal, Mohammadreza Koopialipoor, Panayiotis C. Roussis, Maria Ferentinou, Danial Jahed Armaghani, Behrouz Gordan   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A Novel Attention-Based Generalized Efficient Layer Aggregation Network for Landslide Detection from Satellite Data in the Higher Himalayas, Nepal

Remote Sensing
Landslide event detection poses a significant challenge in the remote sensing community, especially with the advancements in computer vision technology.
Naveen Chandra, Himadri Vaidya, Suraj Sawant, Sansar Raj Meena   +3 more
doaj   +1 more source

Evaluation of the Reinforcement Performance of Loess Slopes Affected by Rainfall Infiltration

Geofluids, 2022
The instability disaster of slope engineering is the third largest geological disaster after earthquake and debris flow, and rainfall is an important factor affecting the stability of slopes.
Yongdong Yang, Hai Liu, Hongfei Li, Shengrui Su, Wanfeng Liu, Yunxiu Dong, Dong Wang   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Landslide topology uncovers failure movements

Nature Communications
The death toll and monetary damages from landslides continue to rise despite advancements in predictive modeling. These models’ performances are limited as landslide databases used in developing them often miss crucial information, e.g., underlying ...
Kushanav Bhuyan, Kamal Rana, Joaquin V. Ferrer, Fabrice Cotton, Ugur Ozturk, Filippo Catani, Nishant Malik   +6 more
doaj   +1 more source

Influence of the Slope Shape on Seismic Stability of a Slope

Advances in Civil Engineering, 2020
The slope shape is one of the most intuitive factors affecting the seismic stability of a slope. However, current research on this subject is mainly focused on statistical analysis and seismic response law, and the influence on seismic stability ...
Zhaopeng Zhang, Chaoyu Chang, Zhiyi Zhao
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Multi-Temporal Satellite Image Composites in Google Earth Engine for Improved Landslide Visibility: A Case Study of a Glacial Landscape

Remote Sensing, 2022
Regional early warning systems for landslides rely on historic data to forecast future events and to verify and improve alarms. However, databases of landslide events are often spatially biased towards roads or other infrastructure, with few reported in ...
Erin Lindsay, Regula Frauenfelder, Denise Rüther, Lorenzo Nava, Lena Rubensdotter, James Strout, Steinar Nordal   +6 more
doaj   +1 more source