Results 51 to 60 of about 187,011 (252)

LSDSAM: Harnessing Visual Foundation Model and Enhanced Transfer Learning Toward Practical Landslide Detection in Few-Shot Scenarios

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Landslides occur frequently in mountainous regions worldwide, emergency management and risk analysis urgently need automated, accurate landslide detection (LSD) techniques.
Zijin Fu, Fawu Wang, Zihan Tu, Xingliang Peng, Guanting Liu, Filippo Catani   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Enhancing landslide detection in Western Ghats of Kerala, India with deep learning and Explainable AI

Scientific Reports
The Western Ghats in Kerala, India, have witnessed a significant rise in landslide occurrences in recent years. More recently in 2024, catastrophic landslides in Wayanad district claimed 336 lives, with 78 people reported missing, underscoring the urgent
Abhilash Sreekumar, Hemalatha Thirugnanam, Sansar Raj Meena, Maneesha Vinodini Ramesh   +3 more
doaj   +1 more source

Influence of the Slope Shape on Seismic Stability of a Slope

Advances in Civil Engineering, 2020
The slope shape is one of the most intuitive factors affecting the seismic stability of a slope. However, current research on this subject is mainly focused on statistical analysis and seismic response law, and the influence on seismic stability ...
Zhaopeng Zhang, Chaoyu Chang, Zhiyi Zhao
doaj   +1 more source

Multi-Temporal Satellite Image Composites in Google Earth Engine for Improved Landslide Visibility: A Case Study of a Glacial Landscape

Remote Sensing, 2022
Regional early warning systems for landslides rely on historic data to forecast future events and to verify and improve alarms. However, databases of landslide events are often spatially biased towards roads or other infrastructure, with few reported in ...
Erin Lindsay, Regula Frauenfelder, Denise Rüther, Lorenzo Nava, Lena Rubensdotter, James Strout, Steinar Nordal   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source