Results 121 to 130 of about 435,657 (302)

The use of a DMT to monitor the stability of the slopes of a clay exploitation pit in the Boom clay in Belgium [PDF]

open access: yes, 2015
In Belgium the Boom Clay is a well known overconsolidated clay formation. This Tertiary clay, with the same geological origin as the London Clay, is used for the fabrication of bricks, roofing tiles. In the article is described how the DMT can be used to
Peiffer, Herman
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Monitoring and evaluating of slope stability for setting out of critical limit at slope stability radar

open access: yesInternational Journal of Geo-Engineering, 2017
El monitoreo y la evaluación de la estabilidad de taludes desempeñan un papel vital en la gestión de riesgos de las minas a cielo abierto. En general, el problema de falla de taludes ocurre en minas a cielo abierto debido a la minería indisciplinada, los impactos de las condiciones climáticas.
Ajay Kumar, Ritika Rathee
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A mobile planetary lander utilizing elastic loop suspension [PDF]

open access: yes, 1976
Efforts to increase the cost effectiveness of future lunar and planetary rover missions have led to the mobile lander concept, which replaces the landing legs of a soft-lander craft with a compact mobility system of sufficient strength to withstand the ...
Trautwein, W.
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

EXPERIMENTAL, ANALYTICAL AND THEORETICAL SLOPE STABILITY ANALYSIS WITH DIFFERENT MATERIALS AND METHODS

open access: yesBoletín de Ciencias de la Tierra, 2010
Slopes are usually constructed from soil, although natural soil or mixed soil are also in use or have proposed. This paper deals with evaluation of slope stability.
ABDOULLAH NAMDAR, AZAM KHODASHENAS PELKO
doaj  

Predicting and evaluating slope stability in permafrost regions of the central Qinghai‒Tibetan Plateau

open access: yesAdvances in Climate Change Research
Thermokarst landslides have frequently occurred in the central Qinghai‒Tibetan Plateau (QTP), endangering infrastructure and the environment. However, there have been no adequate methods to predict thermokarst landslides until now.
Fei Wang   +6 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy