Results 201 to 210 of about 117,118 (314)

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Distinct distributions of myosin motor conformations during contraction of slow and fast skeletal muscle. [PDF]

J Physiol
Hill C, Kalakoutis M, Arcidiacono A, Wang Y, Smith E, Smith E, Brunello E, Fusi L, Irving M.   +8 more
europepmc   +1 more source

Neuromuscular Fatigue and Perceived Fatigability in the Hours Following a High‐Intensity Endurance Running Depend on the Exercise Protocol

European Journal of Sport Science, Volume 26, Issue 8, August 2026.
ABSTRACT This study investigated neuromuscular fatigue and perceived fatigability across different high‐intensity endurance running protocols. Twelve males (mean ± SD; V˙O2max $\dot{\mathrm{V}}{\mathrm{O}}_{2\,\max }$: 52.2 ± 6.9 mL/kg/min) ran ∼8.0 km: (i) at the velocity associated to the respiratory compensation point (vRCP; 5 × 8 min bouts ‒ RUN100%
Yago Medeiros Dutra, Paloma Tavares Mendonça, Stuart Goodall, Alessandro Moura Zagatto   +3 more
wiley   +1 more source

Impact of childbirth mode and interaction of multiple factors on pelvic floor function: a comprehensive analysis of postpartum muscle strength indicators. [PDF]

Front Glob Womens Health
Wang G, Zhang H, Yang X, Yang Y, Ye M, Li Y.   +5 more
europepmc   +1 more source

Genetic landscape of patients with atypical absence status epilepticus: A systematic review

Epilepsia Open, Volume 11, Issue 4, Page 1111-1125, August 2026.
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu, Giada Giovannini, Stefano Meletti   +2 more
wiley   +1 more source

BRD4 directs myofiber identity and metabolic adaptation through CHD4 cooperation. [PDF]

Nat Commun
Zhou Z, Liu L, Xu Z, Zhou D, Liu A, Yuan J, Shen G, Guo Q, Yin Y, Mao Y, Sun W, Xiao L, Lv C, Kiram A, Yang L, Jia Y, Ke L, Fang L, Li W, Fu T, Gan Z.   +20 more
europepmc   +1 more source

The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling

Nature Genetics, 2004
S. Baxendale, C. Davison, C. Muxworthy, C. Wolff, P. Ingham, Sudipto Roy   +5 more
semanticscholar   +1 more source

The Impact of Ageing on Skeletal Muscle: Roles of Mitochondrial Dysregulation, Systemic Communication, and Exercise

Journal of Cellular Physiology, Volume 241, Issue 8, August 2026.
ABSTRACT Ageing is a major risk factor for degenerative diseases, including sarcopenia, which is characterized by a progressive loss of skeletal muscle mass and function, frailty, and is associated with increased mortality. Skeletal muscle regeneration relies on muscle stem cells and efficient communication with cellular microenvironment.
Juan Diego Hernández‐Camacho, Marielle Saclier   +1 more
wiley   +1 more source

Effects of Copper Citrate and Copper Sulfate on Intestinal Health, Muscle Fiber Traits, and Antioxidant Capacity in Weaned Pigs. [PDF]

Animals (Basel)
Chen Z, Long Q, Wang W, Gu Y, Diao H, Zhang Y, Xu M.   +6 more
europepmc   +1 more source

The properties of motor units in a fast and a slow twitch muscle during post‐natal development in the kitten

Journal of Physiology, 1974
J. Bagust, D. M. Lewis, R. Westerman
semanticscholar   +1 more source