Quantitative Spatiotemporal Analysis of Ultrasound Images of Fasciculations in ALS
ABSTRACT Introduction/Aims Fasciculations are a hallmark of amyotrophic lateral sclerosis (ALS), yet quantitative description of individual events on muscle ultrasound (MUS) is limited. We characterized the spatiotemporal kinematics of individual fasciculations to determine whether they differ between ALS and other neurogenic conditions.
Ryosuke Sugisawa +7 more
wiley +1 more source
Hypertrophic cardiomyopathy-linked Tnnc1 variants are associated with distinct myopathic changes in slow skeletal muscle of mice. [PDF]
Patel S +11 more
europepmc +1 more source
ABSTRACT Introduction/Aims Needle electromyography (EMG) in the bulbar region aids in the diagnosis of amyotrophic lateral sclerosis (ALS) but remains technically challenging. The genioglossus muscle (GM) is commonly examined; however, pain and poor relaxation may limit its evaluation.
Tatsuya Fukumoto +5 more
wiley +1 more source
Sarcopenia, cachexia and frailty in older cats: Mechanisms, assessment and therapeutic considerations. [PDF]
Chandler M.
europepmc +1 more source
With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley +1 more source
Guanfacine extended‐release can be an effective monotherapy for adults with ADHD and comorbid tic disorders. A low dose of guanfacine was sufficient to produce a rapid improvement in tic symptoms in each patient before improving ADHD symptoms. ABSTRACT Tic disorders typically begin in childhood and often improve by adulthood, but some individuals ...
Koji Tada +3 more
wiley +1 more source
Effect of monochromatic light combinations on muscle fiber types in broilers after thyroidectomy. [PDF]
Liu Y +7 more
europepmc +1 more source
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles +3 more
wiley +1 more source
A randomized controlled trial of a health literacy-based digital intervention to promote postpartum recovery and self-care. [PDF]
Wang Z, Li Q.
europepmc +1 more source
Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source

