Results 231 to 240 of about 1,504,818 (288)

A Biomimetic 3D Human Skeletal Muscle Microtissue for Modeling Biological and Functional Hallmarks of Aging

open access: yesSmall Science, Volume 6, Issue 9, September 2026.
A biomimetic 3D human skeletal muscle microtissue platform is developed by integrating primary young and aged SkMCs with muscle‐derived dECM and 3D‐printed PCL anchors. Aged constructs recapitulate selected biological and functional hallmarks of skeletal muscle aging, including impaired myotube formation, mitochondrial alterations, calcium handling ...
Sohae Yang   +9 more
wiley   +1 more source

Asymptomatic Carrier Neurologic Assessment: A Tool for Early Detection of Symptomatic Transition in Pathogenic TTR Gene Variant Carriers

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
There are no tools to support early detection of ATTRv signs/symptoms or to identify risk of transition to clinically detectable disease in carriers of pathogenic ATTRv variants. This retrospective cohort study describes the ACNA, a brief 23‐item assessment for use in routine clinical visits.
Isabel Conceição   +8 more
wiley   +1 more source

Future Prospects of Ultrasound: Role of Low‐Intensity Transcranial Ultrasound Stimulation in the Treatment of Neurological and Psychiatric Disorders

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Background Neurological and psychiatric disorders pose a persistent global health burden, with conventional therapies often providing inadequate relief. Transcranial ultrasound stimulation (TUS) has attracted considerable attention as a non‐invasive neuromodulation technique offering high spatial resolution and the distinctive capacity to ...
Yunjie Sui   +3 more
wiley   +1 more source

Development of striated muscle microvasculature across the perinatal period in lambs. [PDF]

open access: yesJ Physiol
Chang EI   +12 more
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

open access: yesThe FEBS Journal, Volume 293, Issue 18, Page 5585-5599, September 2026.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna   +5 more
wiley   +1 more source

Ninjin'yoeito Kampo medicine enhances zebrafish endurance under forced-swimming conditions via muscle hypertrophy. [PDF]

open access: yesJ Nat Med
Hirano K   +9 more
europepmc   +1 more source

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