Results 41 to 50 of about 123,930 (250)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
open design e slow fashion para sustentabilidade do sistema moda
Entre as diversas modalidades de consumo da moda, a fast fashion é muito expressiva. A modalidade caracteriza-se pelo alto impacto ambiental. Logo, o artigo afirma a necessidade de procurar mudanças nas formas de projeto, produção e consumo de moda ...
Priscilla Boff Ferronato, Carlo Franzato
doaj +5 more sources
Entanglements of a Dress Named Laverne: Threads of Meaning between Humans and Things (and Things)
This is a narrative about a dress named Laverne and a woman named Elizabeth told through Ian Hodder’s proposition about entanglements. Elizabeth Withey wrote a blog called Frock Around the Clock about her lived experience of wearing the black dress ...
Jessica Kennedy, Megan Strickfaden
doaj +1 more source
PESQUISA E DESENVOLVIMENTO DE UMA COLEÇÃO DE MODA SLOW FASHION
Uma das indústrias que mais cresce é aquela que envolve produtos de vestuário. Ao longo do século passado (1900 – 2000), o mercado desse tipo de produto tem crescido e junto dele, a competitividade foi ficando mais acirrada.
Marília Matos Gonçalves +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
O protagonismo que as Tecnologias de Informação e Comunicação ganharam na atualidade, fez com que espaços virtuais de inter-relacionamento, como os Serviços de Redes Sociais Online, expandissem as possibilidades de comunicação dos mais diversos grupos ...
Larissa Lima Silva +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Slow Fashion e sua relação com redes sociais
Com foco nos Objetivos de Desenvolvimento Sustentáveis (ODS) da ONU para 2030, especificamente no ODS 12: “Consumo e Produção Responsáveis”, o presente artigo relaciona a conexão entre o “slow fashion” e as mídias sociais.
Íris Malta Silva +1 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

