Results 51 to 60 of about 127,937 (288)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fashion Education in Sustainability: Change Through Experiential Crossings [PDF]
, 2013 Sustainability is distinguished by its multidimensional, messy, big and small transformational change processes that impact the world on all scales and timelines that are both short and long. This is, whilst challenging, full of diverse possibilities. To
Williams, Dilys
core
Slow Design de Superfície e Tecnologias Contemporâneas Aplicados na Moda
ModaPalavra e-periódico, 2018 Este artigo atualiza os conceitos e fundamentos de metodologia projetual do Design de Superfície a partir de abordagem humana e ética, inspirada nos princípios do Slow Design (Strauss e Fuad-Luke, 2008).
Evelise Anicet Ruthschilling +1 more
doaj +5 more sources
TekstilecThe purpose of this study was to identify motivational factors for consumers in making a purchase decision for a fast fashion product. The term fast fashion is used to refer to cheaper replicas of luxury fashion trends.
Sushil Kumar Bishnoi, Ramratan Guru
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A Cognitive and Social Psychological Perspective on the Demand for Fashion [PDF]
, 2014 The fashion industry is an important global industry. In 2012, in Britain it generated more than £48 billion annually and employs more than 600,000 people. Whether or not we consider ourselves fashionable or interested in fashion, we all clothe ourselves
Mair, Carolyn
core
open design e slow fashion para sustentabilidade do sistema moda
ModaPalavra e-periódico, 2015 Entre as diversas modalidades de consumo da moda, a fast fashion é muito expressiva. A modalidade caracteriza-se pelo alto impacto ambiental. Logo, o artigo afirma a necessidade de procurar mudanças nas formas de projeto, produção e consumo de moda ...
Priscilla Boff Ferronato, Carlo Franzato
doaj +5 more sources
Społeczno-ekonomiczne aspekty rozwoju produktów zrównoważonych branży tekstylno-odzieżowej
Zeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie, 2019 W artykule przeprowadzono analizę głównych problemów przemysłu tekstylno-odzieżowego obejmujących społeczno-ekonomiczne aspekty jego funkcjonowania oraz wskazano przykłady działań, które przybliżają tę branżę do zrównoważonego rozwoju.
Mateusz Kowalski, Renata Salerno-Kochan
doaj +1 more source