Results 111 to 120 of about 2,387,223 (285)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Millimeter Wave Localization: Slow Light and Enhanced Absorption
, 2007 We exploit millimeter wave technology to measure the reflection and transmission response of random dielectric media. Our samples are easily constructed from random stacks of identical, sub-wavelength quartz and Teflon wafers.
C. Dahl +10 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Active Control of Slow Light in a Gain-Assisted Plasmon-Induced Transparency Structure
IEEE Photonics Journal, 2017 Plasmon-induced transparency (PIT) in a compact plasmonic resonator structure, which consists of a metal– dielectric–metal waveguide with an aperture-coupled square cavity and a slot resonator, is investigated theoretically and numerically.
Jianhua Yang +4 more
doaj +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Slow light, fast computers [PDF]
Nature Photonics, 2007 As everything else seems to get faster, why are scientists trying to slow light down? David Gevaux spoke to Fengnian Xia and Yurii Vlasov at the IBM Thomas J. Watson Research Center to find out.
openaire +1 more source
Slow Light Enhanced Phase Shifter Based on Low-Loss Silicon-ITO Hollow Waveguide
IEEE Photonics Journal, 2019 An optical phase shifter based on narrow-core hollow waveguide is proposed. The light is guided in an air core between the top and bottom reflectors made up of silicon and indium tin oxide (ITO) gratings. The proposed narrow-core hollow structure is able
Swati Rajput +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Bend Coupling Through Near-Zero GVD Slow Light Photonic Crystal Waveguides
IEEE Photonics Journal, 2018 Slow light propagation through photonic crystal (PhC) slab devices has great potential to reduce the size and power consumption of silicon photonic optical circuits.
Emerson Goncalves Melo +2 more
doaj +1 more source