Results 91 to 100 of about 2,351,070 (299)

Octopus-Inspired Soft Robot for Slow Drug Release

open access: yesBiomimetics
Octopus tentacles are equipped with numerous suckers, wherein the muscles contract and expel air, creating a pressure difference. Subsequently, when the muscular tension is released, objects can be securely adhered to.
Dingwen Tong   +7 more
doaj   +1 more source

Effects of slow-and controlled-release nitrogen fertilizer on nitrogen utilization characteristics and yield of machine-transplanted rice

open access: yes浙江大学学报. 农业与生命科学版, 2015
In order to reduce artificial inputs and improve the efficiency of crop production, the slow- and controlled-release nitrogen (N) fertilizer has become a research focus.
Li Yue   +7 more
doaj   +1 more source

Slow release antibiotics for treatment of septic arthritis in large animals

open access: yes, 2010
The search for an effective treatment for septic arthritis is ongoing. Current therapies are expensive since they require repeated joint lavage and long term antibiotic treatment.
Judith Habermacher   +9 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Propagation loss in slow light photonic crystal waveguides [PDF]

open access: yes, 2012
The field of nanophotonics is a major research topic, as it offers potential solutions to important challenges, such as the creation of low power, high bandwidth interconnects or optical sensors.
Schulz, Sebastian Andreas
core   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The Fifth Series of Wiltshire Rhymes and Tales in the Wiltshire Dialect. [PDF]

open access: yes, 1894
Literatura Dialectal Inglesa. -- Wiltshire. -- Pertenece a la colección 1800-1950 del Salamanca Corpus. -- Verso. -- Prosa. -- Edward Slow, 1841-1925. -- The Fifth Series of Wiltshire Rhymes and Tales in the Wiltshire Dialect.
Slow, Edward, 1841-1925
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Efficacy and safety of different doses of a slow release corticosteroid implant for macular edema

open access: yes, 2016
John Hall Medical Affairs, Alimera Sciences Ltd., Aldershot, Hampshire, UKI read “Efficacy and safety of different doses of a slow release corticosteroid implant for macular edema: meta-analysis of randomized controlled trials” published in ...
Hall J
core  

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