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Effect of Microstructural Constituents on Hydrogen Embrittlement Resistance of API X60, X70, and X80 Pipeline Steels [PDF]
Archives of Metallurgy and MaterialsThis study describes how microstructural constituents affected the hydrogen embrittlement resistance of high-strength pipeline steels. The American Petroleum Institute (API) X60, X70, and X80 pipeline steels demonstrated complicated microstructure ...
Seung-Hyeok Shin +3 more
doaj +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Deposition of Nickel-tungsten-phosphorus Coatings on Pure Copper in a Saline Water Environment
International Journal of Electrochemical Science, 2021 Corrosion of copper caused by chloride species restricts advances in the maritime industry. In the present study, ternary Ni-W-P alloys were electrodeposited on copper in DC current mode to improve the corrosion resistance of the matrix.
Pei-Jing Teng +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Materials Research Express, 2022 Hydrogen blended with natural gas is one of the best ways for large-scale hydrogen transportation; however, pipeline steels exploited for transferring natural gas have the risk of hydrogen embrittlement.
Liuxi Cai +4 more
doaj +1 more source
Nihon Kikai Gakkai ronbunshu, 2021 The evaluation of delayed fracture is essential owing to the widespread application of high-strength steel to reduce automotive weight. Furthermore, it is necessary to clarify the influence of local stress concentration at the notch root as delayed ...
Aya TSUJI +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source