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A noninvasive test for human prion disease using hair roots and scalp [PDF]

open access: yesScientific Reports
Invasive tests like cerebrospinal fluid (CSF) examination are highly effective for diagnosing human prion disease (HPD). Real-time quaking-induced conversion (RT-QuIC) CSF assay demonstrates 80–90% sensitivity for HPD diagnosis.
Thi-Thu-Trang Dong   +29 more
doaj   +2 more sources

SLOW VIRUS DISEASES OF THE CENTRAL NERVOUS SYSTEM [PDF]

open access: bronzePediatric Research, 1980
During the last 3 decades a new concept of an infectious process has been derived by studying certain Central Nervous System (CNS) diseases in animals. These infections are characterized by an incubation period lasting for many months to years and by a predictable, protracted clinical course usually leading to death.
Volker ter Meulen
openaire   +2 more sources

Slow virus diseases in sheep and goats

open access: diamondSuid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie, 1984
Ethel‐Michele de Villiers
openaire   +3 more sources

The Viral Threat in Cotton: How New and Emerging Technologies Accelerate Virus Identification and Virus Resistance Breeding

open access: yesFrontiers in Plant Science, 2022
Cotton (Gossypium spp. L., Malvaceae) is the world’s largest source of natural fibers. Virus outbreaks are fast and economically devasting regarding cotton.
Roberto Tarazi   +3 more
doaj   +1 more source

Hindlimb muscle representations in mouse motor cortex defined by viral tracing

open access: yesFrontiers in Neuroanatomy, 2023
IntroductionDescending pathways from the cortex to the spinal cord are involved in the control of natural movement. Although mice are widely used to study the neurobiology of movement and as models of neurodegenerative disease, an understanding of motor ...
Lauren Maurer   +8 more
doaj   +1 more source

AAV Vector-Mediated Antibody Delivery (A-MAD) in the Central Nervous System

open access: yesFrontiers in Neurology, 2022
In the last four decades, monoclonal antibodies and their derivatives have emerged as a powerful class of therapeutics, largely due to their exquisite targeting specificity.
Marika Marino   +5 more
doaj   +1 more source

Ebola Virus Disease, Diagnostics and Therapeutics: Where is the Consensus in Over Three Decades of Clinical Research?

open access: yesScientific African, 2021
Ebola virus is a neglected tropical disease widely accepted as one of the most fatal diseases of human and nonhuman primates ever encountered in recent years. For a long time, development of vaccines and anti-Ebola drugs has been slow.
Collins Kipkorir Kebenei, Patrick Okoth
doaj   +1 more source

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