The Impact of Covid-19 on Future Higher-Age Mortality [PDF]
, 2020 Covid-19 has predominantly affected mortality at high ages. It kills by inflaming and clogging the air sacs in the lungs, depriving the body of oxygen ‒ inducing hypoxia ‒ which closes down essential organs, in particular the heart, kidneys and liver ...
Blake, D. +3 more
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Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR [PDF]
, 2019 The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who ...
Berenguer, Juan +14 more
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Breed Differences in PCV2 Uptake and Disintegration in Porcine Monocytes
Viruses, 2018 Porcine circovirus type 2 (PCV2) is associated with various diseases which are designated as PCV2-associated diseases (PCVADs). Their severity varies among breeds.
Ruifang Wei +4 more
doaj +1 more source
Liver organoids: an in vitro 3D model for liver cancer study
Cell & Bioscience, 2022 Primary liver cancer (PLC) is the second leading cause of cancer mortality worldwide, and its morbidity unceasingly increases these years. Hepatitis B virus (HBV) infection accounted for approximately 50% of hepatocellular carcinoma (HCC) cases globally ...
Renshun Dong, Bixiang Zhang, Xuewu Zhang
doaj +1 more source
The Zika outbreak of the 21st century. [PDF]
, 2016 The Zika virus outbreak has captivated the attention of the global audience and information has spread rapidly and wildly through the internet and other media channels.
Ansari, Aftab +3 more
core +1 more source
Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19
Frontiers in Aging, 2021 Aging has emerged as the greatest and most prevalent risk factor for the development of severe COVID-19 infection and death following exposure to the SARS-CoV-2 virus.
Alan Landay +27 more
doaj +1 more source
Characterising two-pathogen competition in spatially structured environments
, 2014 Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space structure of the ...
Colizza, Vittoria +5 more
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Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
, 2015 Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
core +3 more sources
In silico Drug Screening Approach Using L1000-Based Connectivity Map and Its Application to COVID-19
Frontiers in Cardiovascular Medicine, 2022 Conventional drug screening methods search for a limited number of small molecules that directly interact with the target protein. This process can be slow, cumbersome and has driven the need for developing new drug screening approaches to counter ...
Takaharu Asano +10 more
doaj +1 more source
The Social and Political Dimensions of the Ebola Response: Global Inequality, Climate Change, and Infectious Disease [PDF]
, 2016 The 2014 Ebola crisis has highlighted public-health vulnerabilities in Liberia, Sierra Leone, and Guinea – countries ravaged by extreme poverty, deforestation and mining-related disruption of livelihoods and ecosystems, and bloody civil wars in the ...
A Kay +41 more
core +1 more source