Results 41 to 50 of about 1,274,311 (192)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Thalamic involvement defines distinct slow-wave subtypes in NREM sleep
Communications BiologySlow waves (0.5–2 Hz) are a key feature of non-rapid-eye-movement (NREM) sleep, traditionally believed to arise from neocortical circuits. However, growing evidence suggests that subcortical structures, particularly the thalamus, may play a crucial role ...
Damiana Bergamo +9 more
doaj +1 more source
Physics, 2023 Solar chromosphere and photosphere, as well as solar atmospheric structures, such as prominences and spicules, are made of partially ionized plasmas.
José Luis Ballester
doaj +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
FEBS Open Bio, EarlyView.Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Slow and Fast Neocortical Oscillations in the Senescence-Accelerated Mouse Model SAMP8
Frontiers in Aging Neuroscience, 2017 The senescence-accelerated mouse prone 8 (SAMP8) model is characterized by accelerated, progressive cognitive decline as well as Alzheimer’s disease (AD)-like neurodegenerative changes, and resembles the etiology of multicausal, sporadic late-onset/age ...
Patricia Castano-Prat +5 more
doaj +1 more source
Boosting Recovery During Sleep by Means of Auditory Stimulation
Frontiers in Neuroscience, 2022 Sufficient recovery during sleep is the basis of physical and psychological well-being. Understanding the physiological mechanisms underlying this restorative function is essential for developing novel approaches to promote recovery during sleep.
Elena Krugliakova +11 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Simulating ultracold matter: horizons and slow light [PDF]
, 2007 This thesis explores the links between different ways of modelling the physical world. Finite difference numerical simulations may be used to encode the behaviour of physical systems, allowing us to gain insight into their workings and even to predict ...
Farrell, Conor, Conor Farrell
core +2 more sources
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
BMC Medical Genomics, 2020 Background The microdeletion of chromosome 13 has been rarely reported. Here, we report a 14-year old Asian female with a de novo microdeletion on 13q12.3.
Mina Wang +4 more
doaj +1 more source