Results 101 to 110 of about 6,925,642 (276)
Limit distributions of vertex degrees in a conditional configuration graph
The configuration graph where vertex degrees are independent identically distributed random variables is often used for modeling of complex networks such as the Internet. We consider a random graph consisting of N vertices.
Irina Chepliukova, Yuri Pavlov
doaj +1 more source
Functional limit theorems for the Bouchaud trap model with slowly varying traps
We consider the Bouchaud trap model on the integers in the case that the trap distribution has a slowly varying tail at infinity. Our main result is a functional limit theorem for the model under the annealed law, analogous to the functional limit theorems previously established in the literature in the case of integrable or regularly varying trap ...
David Croydon, Stephen Muirhead
openaire +2 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Flesh-Colored Papules on the Glans Penis
A 23-year-old man reported a 3-year history of slowly growing, slightly itchy, flesh-colored papules on the distal glans penis. He denied any history of trauma or previous treatment. Additionally, he experienced no difficulties with urination, discharge,
Phatcharawat Chirasuthat +2 more
doaj +1 more source
A holographic cut-off inspired in the apparent horizon
In this work we consider a general function for the $$c^{2}$$ c2 term that appears in the conventional expression for the holographic dark energy in a FLRW curved spacetime. The cut-off prospective is inspired in the apparent horizon length. By exploring
Miguel Cruz, Samuel Lepe
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Multiuser Delay-Tracking CDMA Receiver
We propose to integrate delay tracking into a successive interference cancellation (SIC) code division multiple access (CDMA) multiuser detector. Delay-robust SIC was initially proposed for CDMA multiuser detection when there exist time delay estimation
Zha Wei, Blostein Steven D
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

