Results 61 to 70 of about 631,519 (293)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

GENOME-BASED MODELING AND DESIGN OF METABOLIC INTERACTIONS IN MICROBIAL COMMUNITIES

open access: yesComputational and Structural Biotechnology Journal, 2012
Biotechnology research is traditionally focused on individual microbial strains that are perceived to have the necessary metabolic functions, or the capability to have these functions introduced, to achieve a particular task.
Radhakrishnan Mahadevan   +1 more
doaj   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Slow feature analysis yields a rich repertoire of complex cell properties [PDF]

open access: yes, 2003
In this study, we investigate temporal slowness as a learning principle for receptive fields using slow feature analysis, a new algorithm to determine functions that extract slowly varying signals from the input data.
Berkes, Pietro, Wiskott, Laurenz
core  

Singularity of Berry Connections Inhibits the Accuracy of Adiabatic Approximation

open access: yes, 2006
Adiabatic approximation for quantum evolution is investigated quantitatively with addressing its dependence on the Berry connections. We find that, in the adiabatic limit, the adiabatic fidelity may uniformly converge to unit or diverge manifesting the ...
Anderson   +38 more
core   +1 more source

Super-Slowly Varying Functions in Extreme Value Theory

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1978
Summary Large-deviation limit theorems for maxima of random samples in the domain of attraction of the extreme value distribution Φα are studied, motivated by examination of an approximation used in the statistical analysis of large observations.
openaire   +2 more sources

Augmented brain function by coordinated reset stimulation with slowly varying sequences

open access: yesFrontiers in Systems Neuroscience, 2015
Several brain disorders are characterized by abnormally strong neuronal synchrony. Coordinated Reset (CR) stimulation was developed to selectively counteract abnormal neuronal synchrony by desynchronization. For this, phase resetting stimuli are delivered to different subpopulations in a timely coordinated way.
Magteld eZeitler   +3 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Applicability of the Analytical Solution to N-Person Social Dilemma Games

open access: yesFrontiers in Applied Mathematics and Statistics, 2018
The purpose of this study is to present an analysis of the applicability of an analytical solution to the N−person social dilemma game. Such solution has been earlier developed for Pavlovian agents in a cellular automaton environment with linear payoff ...
Ugo Merlone   +2 more
doaj   +1 more source

Perturbative dynamics on fuzzy S^2 and RP^2

open access: yes, 2001
By considering scalar theories on the fuzzy sphere as matrix models, we construct a renormalization scheme and calculate the one-loop effective action. Because of UV-IR mixing, the two- and the four-point correlators at low energy are not slowly varying ...
Baez   +17 more
core   +1 more source

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