Results 61 to 70 of about 631,519 (293)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
GENOME-BASED MODELING AND DESIGN OF METABOLIC INTERACTIONS IN MICROBIAL COMMUNITIES
Biotechnology research is traditionally focused on individual microbial strains that are perceived to have the necessary metabolic functions, or the capability to have these functions introduced, to achieve a particular task.
Radhakrishnan Mahadevan +1 more
doaj +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Slow feature analysis yields a rich repertoire of complex cell properties [PDF]
In this study, we investigate temporal slowness as a learning principle for receptive fields using slow feature analysis, a new algorithm to determine functions that extract slowly varying signals from the input data.
Berkes, Pietro, Wiskott, Laurenz
core
Singularity of Berry Connections Inhibits the Accuracy of Adiabatic Approximation
Adiabatic approximation for quantum evolution is investigated quantitatively with addressing its dependence on the Berry connections. We find that, in the adiabatic limit, the adiabatic fidelity may uniformly converge to unit or diverge manifesting the ...
Anderson +38 more
core +1 more source
Super-Slowly Varying Functions in Extreme Value Theory
Summary Large-deviation limit theorems for maxima of random samples in the domain of attraction of the extreme value distribution Φα are studied, motivated by examination of an approximation used in the statistical analysis of large observations.
openaire +2 more sources
Augmented brain function by coordinated reset stimulation with slowly varying sequences
Several brain disorders are characterized by abnormally strong neuronal synchrony. Coordinated Reset (CR) stimulation was developed to selectively counteract abnormal neuronal synchrony by desynchronization. For this, phase resetting stimuli are delivered to different subpopulations in a timely coordinated way.
Magteld eZeitler +3 more
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Applicability of the Analytical Solution to N-Person Social Dilemma Games
The purpose of this study is to present an analysis of the applicability of an analytical solution to the N−person social dilemma game. Such solution has been earlier developed for Pavlovian agents in a cellular automaton environment with linear payoff ...
Ugo Merlone +2 more
doaj +1 more source
Perturbative dynamics on fuzzy S^2 and RP^2
By considering scalar theories on the fuzzy sphere as matrix models, we construct a renormalization scheme and calculate the one-loop effective action. Because of UV-IR mixing, the two- and the four-point correlators at low energy are not slowly varying ...
Baez +17 more
core +1 more source

