Slug-flow microchannel enables efficient and controllable preparation of sensitive protein nanoparticles. [PDF]
Gao Z +13 more
europepmc +1 more source
Effect of Sand Fines Concentration on the Erosion-Corrosion Mechanism of Carbon Steel 90° Elbow Pipe in Slug Flow. [PDF]
Khan R +8 more
europepmc +1 more source
Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park +5 more
wiley +1 more source
Leveraging an intelligent slug flow platform for self-optimization of reaction systems with categorical variables. [PDF]
Wagner FL +6 more
europepmc +1 more source
ABSTRACT Autologous cell therapy (AuCT) manufacturing networks must balance two competing objectives: reducing cost and improving patient access to time‐sensitive therapy. This study compares three AuCT manufacturing network designs: a centralized network with a single manufacturing facility, a coordinated point‐of‐care (POC) network in which POCs can ...
Zhaowei Li +3 more
wiley +1 more source
Experimental and Numerical Study of Slug-Flow Velocity Inside Microchannels Through In Situ Optical Monitoring. [PDF]
Moscato S +3 more
europepmc +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Artificial intelligence-enabled microfluidic cytometer using gravity-driven slug flow for rapid CD4+ T cell quantification in whole blood. [PDF]
Dixit DD +3 more
europepmc +1 more source
ABSTRACT In response to growing global challenges, this study explores how social entrepreneurship within the Edible City movement contributes to building resilient, sustainable, and equitable urban food systems. Drawing on semistructured interviews with over 70 stakeholders across five cities—Berlin, Andernach, Oslo, Rotterdam, and Havana—we ...
Ina Säumel +6 more
wiley +1 more source
Gas transportation in deepwater gas fields includes two primary modes: single⁃pipeline transportation and dual-pipeline transportation. The single-pipeline transportation mode boasts distinct advantages, including low capital investment and a short ...
Li Pengcheng +4 more
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