Results 171 to 180 of about 9,502,534 (376)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Euphorbiaceae Cactaceaeque novae vel criticae colombianae.- I
The botanical investigations now so vigorously conducted in the Republic of Colombia bring forth a continuous stream of novelties or critical forms in the Euphorbiaceae and the Cactaceae, which it is the purpose of these and following notes to describe ...
Croizat Léon
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Con el orgullo de colombiano y de Rector de la Universidad Nacional, doy testimonio de la dedicacion, perseverancia, amor a la ciencia y a la patria, de Los profesores del Instituto de Ciencias Naturales, emblema de La comunidad cientifica nacional.
Palacios Marco
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Zamia huilensis Calonje, Esquivel, & D.W. Stev., a new arborescent species from theEastern Cordillera of Colombia (Department of Huila), is described and illustrated. Itis compared to Z.
Calonje Michael +4 more
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Inventario de las aves de un bosque altoandino: comparación de dos métodos
Capturing birds with mist-nets has been the sole method used or proposed for making species inventories of several Neotropical forests, but this method has rarely been evaluated relative to the use of visual and auditory observations in these forests ...
Stiles Hurd Frank Galfierd +1 more
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PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The mouthpart deformities of chironomid larvae are considered as indicators ofenvironmental stress caused by water pollution such as heavy metals, pesticides, butas well by organic contamination.
RISS WOLFGANG +2 more
doaj

