Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai+2 more
wiley +1 more source
THE EVALUATION TECHNIQUE OF SPEAKINGSUBJECT OF THE SECOND YEAR STUDENTS ATPRIVATE SMAs IN MALANG [PDF]
Speaking ability regards as the most important use in the target language learning because, the objective of learning a foreign language is to use the target language in real communication.
SUSILAWATI, INDAH
core
Genetic studies of acute infantile spinal muscular atrophy (SMA type I). An analysis of sex ratios, segregation ratios, and sex influence. [PDF]
John Pearn
openalex +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
A review of imaging techniques for plant disease detection
Agriculture is the basis of every economy worldwide. Crop production is one of the major factors affecting domestic market condition in any country.
Vijai Singh, Namita Sharma, Shikha Singh
doaj
Moment properties of estimators for an extreme value regression model with type 2 censoring [PDF]
An extreme value regression model for grouped data with type 2 censoring is considered. The response variable is taken to have a type 1 ext reme va lue d i s t r i b u t i on for sma l l e s t v a l ue s a nd a s tandar d linear regression model is ...
Haddow, AA, Young, DH
core
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source