Results 181 to 190 of about 9,502,534 (376)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Estudios ecológicos en la Cordillera Oriental IV: Aspectos sinecológicos de la brioflora de los depósitos turbosos paramunos de los alrededores de Bogotá Estudios ecológicos en la Cordillera Oriental IV: Aspectos sinecológicos de la brioflora de los depósitos turbosos paramunos de los alrededores de Bogotá

open access: yesCaldasia, 1989
Mediante los lineamientos metodológicos de la escuela Zurich-Montpellier (Braun-Blanquet, 1979) se realizaron 102 levantamientos de la vegetación que se establece en los pantanos, turberas o depósitos turbosos de los páramos de los alrededores de Bogotá.
Sánchez M. Roberto   +2 more
doaj  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Estudios sobre plantas andinas, III

open access: yesCaldasia, 1942
Puya lepidota / TYPUS ...
Cuatrecasas José
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Una nueva especie de Microteido (Sauria: Teiidae) del oriente de Colombia Una nueva especie de Microteido (Sauria: Teiidae) del oriente de Colombia

open access: yesCaldasia, 1982
A new microteiid species is described from two sites in Colombia's Orinoco River Basin near the eastern border with Venezuela. The other Colombian Leposoma species have leaf-shaped dorsal scales, but in the new taxon they are keeled, elongate and ...
Ayala Stephen C., Harris Dennis M.
doaj  

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