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Imaging Devices for Use in Small Animals
Seminars in Nuclear Medicine, 2011Imaging devices for small animals have emerged in the past 10 years as extraordinarily useful tools in translational research and drug development. The Food and Drug Administration requires animal testing after in vitro drug discovery but before human application.
Wade, Koba +6 more
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Small animal imaging with multi-pinhole SPECT
Methods, 2009With Single Photon Emission Computed Tomography (SPECT), images of minute concentrations of tracer molecules can be acquired, allowing in vivo molecular imaging. For human imaging, the SPECT system has a modest spatial resolution of 5-15 mm, a large field of view and a high sensitivity.
Nuyts, Johan +3 more
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Quantification of Small-Animal Imaging Data
2014The field of molecular imaging finds its roots in nuclear medicine, which since its inception had a major focus on task-based optimization of image quality, and on in vivo quantitative assessment of metabolic and physiological parameters [1]. This standpoint reflects the limited spatial resolution and high noise characteristics of SPECT and PET ...
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Optical tomographic imaging of small animals
Current Opinion in Biotechnology, 2005Diffuse optical tomography is emerging as a viable new biomedical imaging modality. Using visible and near-infrared light this technique can probe the absorption and scattering properties of biological tissues. The main applications are currently in brain, breast, limb and joint imaging; however, optical tomographic imaging of small animals is ...
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Towards quantitative small-animal imaging on hybrid PET/CT and PET/MRI systems
Clinical and translational imaging, 2020Mahsa Amirrashedi, H. Zaidi, M. Ay
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Small animal imaging with a clinical magnetic resonance imager
Magnetic Resonance in Medicine, 1987AbstractAny clinical whole‐body MR imager can be adapted for experimental small animal imaging. The design of an if receiver coil and an efficient magnified imaging technique are presented. Application of this small animal imaging technique is illustrated using a study of paramagnetic contrast enhancement of a tumor in the mouse. © 1987 Academic Press,
R M, Henkelman +2 more
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Design and testing of a 750MHz CW-EPR digital console for small animal imaging.
Journal of magnetic resonance (San Diego, Calif. 1997 : Print), 2017H. Sato-Akaba +3 more
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The biological application of small animal PET imaging
Nuclear Medicine and Biology, 2001The short history of small animal PET is reviewed in the context of its application in the laboratory. Early work has demonstrated a role for the technique in both drug development and in the in vivo monitoring of neuroreceptor function with time. As spatial resolution approaches 1 mm, challenges in quantification remain.
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