Results 81 to 90 of about 5,855,904 (273)

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Spinal Neuronavigation for Lumbar Plate Fixation in Miniature Breed Dogs. [PDF]

OBJECTIVE  The main aim of this pilot study was to assess the feasibility of spinal neuronavigation for plate fixation of lumbar vertebrae in miniature breed dogs using a surgical navigation system in combination with a custom-made reference array.
Guevar, Julien, Schweizer, Daniela, Müller, Andrea, Papacella-Beugger, Angela, Samer, Eva, Progin, Alexia, Planchamp, Bastien, Forterre, Franck   +7 more
core   +2 more sources

Spatial Problem-Solving in Working Dogs: The Combined Effect of Body-Size Awareness, Social Learning and Functional Breed Selection

Animals
Cooperative and independently working dog breeds differ in the extent of their reliance on human-given instructions; thus, they are ideal subjects for investigating dog–human interactions in a biologically relevant way.
Petra Dobos, Péter Pongrácz
doaj   +1 more source

Breed does not affect the association between murmur intensity and disease severity in dogs with pulmonic or subaortic stenosis

, 2019
Objectives To determine whether breed affects the ability of murmur intensity to predict the severity of stenosis in dogs with pulmonic stenosis or subaortic stenosis.
Ljungvall, Ingrid,, Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

Refractive errors in mixed breed dogs of different ages

, 2023
The purpose of the study was to evaluate the occurrence and range of refractive errors in dogs of different ages. A total of 99 clinically healthy, mixed-breed mesocephalic dogs were included in the study and divided into three different age groups ...
I Balicki, A Balicka, M Szadkowski, J Zwolska, A Trbolova   +4 more
core   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

2013 CVM News: Small breed dogs with healthy hearts invited to participate in project

, 2013
This news item is about: Cornell’s College of Veterinary Medicine invites you to participate in a complimentary veterinary cardiology screening on March 22 and 23 as part of a collaborative project that will further our understanding of mitral valve ...
Office of Marketing and Communications. Media Relations
core   +4 more sources

Myxomatous Mitral Valve Disease in Large Breed Dogs: Survival Characteristics and Prognostic Variables

Veterinary Sciences
Myxomatous mitral valve disease (MMVD) is the most common acquired heart disease in dogs and its occurrence in small-and medium-sized dogs has been extensively investigated.
Mikael Svensson, Jonas Selling, Mark Dirven   +2 more
doaj   +1 more source

Splenic mass diagnosis in dogs undergoing splenectomy according to breed size: 234 dogs (2008-2017)

, 2019
Various splenic diseases can result in a splenic mass and necessitate splenectomy. The objective of this study was to compare the prevalence of malignant and benign splenic diseases, and type of malignant disease, in dogs categorised by breed size.
Hosgood, G., O'Byrne, K., O'Bryne, K.
core  

Domestic dog attacks on sheep in the urban fringe areas of Perth, Western Australia [PDF]

, 2002
In common with many cities, Perth, Western Australia has a problem with domestic dogs attacking livestock, such as sheep on its urban fringe areas. The current study used multiple sources to document 1479 attacks on livestock on 1105 properties by 1900 ...
Jennens, Garth
core