Results 101 to 110 of about 13,064,150 (304)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Emergent Properties in Small-Scale Societies [PDF]
Artificial Life, 2003 A multi-agent simulation is used to explore the relationship between the micro and the macro levels in small-scale societies. The simulation demonstrates, using an African hunter-gatherer group (the !Kung san) as a case study, the way in which population stability may arise from culturally framed, micro-level decision making by women about spacing of ...
openaire +4 more sources
Exchange Rates and Inflation Dynamics in Multicurrency Regimes: The Case of Zimbabwe (2014 to 2024)
International Journal of Financial StudiesExchange rate volatility has emerged to be one of the most critical determinants of price stability for countries operating in multicurrency systems with their own currency in the basket of currencies.
Simion Matsvai
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Open Research EuropeBackground Extended Reality (XR) technologies offer transformative potential for language education, yet current platforms largely neglect the accessibility needs of deaf and hard-of-hearing ...
Nikolaos D. Tantaroudas +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Tax breaks for the small scale sector: An appraisal. [PDF]
Small scale sector ...
Rao, R. Kavita +2 more
core
Building organisational vehicles for smallholder-led agricultural development in sub-Saharan Africa
Discover SustainabilityCivil society organisations play numerous key roles in governing and practically enacting sustainable development. For rural development this importantly includes farmer-based organisations, which among other things can represent and amplify farmers ...
Ellinor Isgren +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source