Results 231 to 240 of about 13,064,150 (304)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Molecular Characterization and Prevalence of <i>Trypanozoon</i> Infection in Livestock on Small-Scale Farms in Thailand: An Integrative Control Approach. [PDF]

Pathogens
Rudeekiatthamrong A, Jhaiaun P, Nguyen GT, Chimnoi W, Chuensaengarun D, Rungchalermlak C, Mutchimadilok T, Thammasonthijarern N, Phannithi T, Apichaimongkonkun T, Apinantanakorn L, Phetudomsinsuk K, Inpankaew T, Nimsuphan B, Ngasaman R, Manojai N, Phasuk J, Kamyingkird K.   +17 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

NeuraEngineDx: An IoT condition monitoring device for Small-Scale fishing vessel engines. [PDF]

HardwareX
Priharanto YE, Jaya I, Rahmat A, Dewi Hardhienata MK, Panggabean D.   +4 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Parasitic Contamination of Fresh Vegetables Marketed and Cultivated in Small-Scale Farms in Hosanna Town and Its Surrounding Areas, Hadiya Zone, Ethiopia. [PDF]

J Parasitol Res
Yohannes G, Gebremariam A, Baraki Y.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Effects of Processing Practices (Boiling and Drying) on the Nutritional, Microbial, and Physical Quality Attributes of Small Fish (<i>Dagaa</i>) in Small-Scale Fishery Systems. [PDF]

Food Sci Nutr
Ngwenyama P, Kitabi P, Tunje D, Masoud E, Odhiambo P, Parmar A, Kimani P.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Social impact of a small-scale sporting event: the case of GIMNASTRADA 2019 in a world Heritage city. [PDF]

Front Sports Act Living
Luis-Del Campo V, Muñoz-Jiménez J, Jiménez-Naranjo HV, León-Guzmán KF.   +3 more
europepmc   +1 more source