Results 101 to 110 of about 19,700,178 (306)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Production of small-scale Alfvén waves by ionospheric depletion, nonlinear magnetosphere-ionosphere coupling and phase mixing [PDF]
, 2013 The authors acknowledge the International Space Science Institute (Switzerland) for funding the program that inspired this work. AJBR is grateful to the Royal Commission for the Exhibition of 1851 for present support and acknowledges an STFC studentship ...
Russell, A. J.B. +9 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Feasibility of large-scale power plants based on thermoelectric effects
New Journal of Physics, 2014 Heat resources of small temperature difference are easily accessible, free and enormous on the Earth. Thermoelectric effects provide the technology for converting these heat resources directly into electricity.
Liping Liu
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Integrating gender into small-scale irrigation
, 2021 Small-Scale Irrigation (SSI) interventions, like other development interventions, need to take into account men’s and women’s context-specific roles in agriculture and their related gender-based preferences and challenges.
http://orcid.org/0000-0003-4277-7080 Theis, Sophie; http://orcid.org/0000-0002-0906-222X Bryan, Elizabeth; http://orcid.org/0000-0002-8266-0488 Ringler, Claudia; http://orcid.org/0000-0003-4782-3074 Meinzen-Dick, Ruth +1 more
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Effectiveness of beads for tracking small-scale molecular motor dynamics
Physical Review E, 2011 Investigations into molecular motor dynamics are increasingly focused on small-scale features of the motor's motion. We define performance measures of a common type of single-molecule motility assay, the bead assay, for its ability to detect such features.
Lade, Steven +2 more
openaire +4 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Scale effects in HRM Research [PDF]
The lack of scientific attention for HRM within SMEs can be seen as a scale effect in HRM research. In addition, two more scale effects can be identified: scale effects in the actual management of human resources and scale effects in the impact of HRM ...
Monique Smolders +2 more
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