Results 141 to 150 of about 19,700,178 (306)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Mercury Pollution Due to Small-Scale Gold Mining in the Philippines: An Economic Analysis [PDF]
The study reviews small-scale gold mining in the Philippines and assesses economically mercury pollution and other development problems of the industry.
Asirot, Jasminda, Israel, Danilo C.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Small-scale fisheries of San Miguel Bay, Philippines: options for management and research [PDF]
Small scale fisheries, Fishery management, San Miguel Bay, Philippines,
Pauly, D., Mines, A.N., Smith, I.R.
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Settlement Issues and Their Effects on Small-Scale Structures
Abstract: Subsidence in low-rise buildings is a significant structural issue caused by factors such as soil composition, water table fluctuations, and human activities. This paper examines the causes, effects, and mitigation strategies for subsidence, emphasizing its consequences, including structural instability, cracking, and safety hazards.
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Small Scale Plasticity With Confinement and Interfacial Effects [PDF]
, 2016 The mechanical properties of crystalline metals are strongly affected when the sample size is limited to the micron or sub-micron scale. At these scales, the mechanical properties are enhanced far beyond classical predictions. Besides, the surface to volume ratio significantly increases.
openaire
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Small-scale fisheries of San Miguel Bay, Philippines: economics of production and marketing [PDF]
Small scale fisheries, Fishery economics, Marketing, Collected papers, San Miguel Bay, Philippines,
Mines, A.N. (eds.), Smith, I.R.
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