Results 91 to 100 of about 9,653,323 (301)

Assessing discards in an illegal small-scale fishery using fisher-led reporting. [PDF]

open access: yesRev Fish Biol Fish, 2022
Mendo T   +13 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Harvest Strategies for an Ecosystem Approach to Fisheries Management in Western Mediterranean Demersal Fisheries

open access: yesFrontiers in Marine Science, 2017
The serious overfishing of most Mediterranean stocks demands urgent reforms of the management measures aiming to guarantee the sustainability of resources, notably when compared with the improvement observed in other European areas.
Antoni Quetglas   +9 more
doaj   +1 more source

Fisheries local action groups, small‐scale fisheries and territorial development

open access: yesSociologia Ruralis
AbstractIn comparison to the wealth of critical evaluation of LEADER (i.e., Liaison entre actions de développement de l'économie rurale), there has been no consolidated attempt to reflect on the contribution of Fisheries Local Action Groups (FLAGs), now entering their third EU programming period.
Jeremy Phillipson   +4 more
openaire   +2 more sources

Philippine municipal fisheries: a review of resources, technology, and socio-economics [PDF]

open access: yes
Small scale fisheries, Sociological aspects, Fishery economics, Fishery management, Philippines,
Vidal-Libunao, C.N.   +2 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Preliminary lessons from COVID-19 disruptions of small-scale fishery supply chains. [PDF]

open access: yesWorld Dev, 2021
Bassett HR   +5 more
europepmc   +1 more source

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