Results 71 to 80 of about 9,653,323 (301)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Evaluating the bio-economic performance of a Callo de hacha (Atrina maura, Atrina tuberculosa & Pinna rugosa) fishery restoration plan in La Paz, Mexico.

PLoS ONE, 2018
Small-scale fisheries are large contributors to regional economies and livelihoods in coastal communities of Latin America. While Mexico is one of the cases where small-scale fisheries play an important role, overfishing and poor management strategies ...
Juliano Palacios-Abrantes, Juliana Herrera-Correal, Salvador Rodríguez, Jacy Brunkow, Renato Molina   +4 more
doaj   +1 more source

Small-scale fisheries of San Miguel Bay, Philippines: economics of production and marketing [PDF]

Small scale fisheries, Fishery economics, Marketing, Collected papers, San Miguel Bay, Philippines,
Mines, A.N. (eds.), Smith, I.R.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A time series analysis of Prochilodus nigricans landings caught by small-scale fisheries in the lower stretch of the Amazon River

Brazilian Journal of Biology
We developed a time series analysis using data on curimatã (Prochilodus nigricans), which landed in Santarém, a small city located on the right banks of the Amazon River. A 10-year record of monthly average catches per day of P.
IF. Santana, CEC. Freitas
doaj   +1 more source

Illuminating the multidimensional contributions of small-scale fisheries

Nature
Sustainable development aspires to "leave no one behind"1. Even so, limited attention has been paid to small-scale fisheries (SSF) and their importance in eradicating poverty, hunger and malnutrition. Through a collaborative and multidimensional data-driven approach, we have estimated that SSF provide at least 40% (37.3 million tonnes) of global ...
Xavier Basurto, Nicolas L. Gutierrez, Nicole Franz, Maria del Mar Mancha-Cisneros, Giulia Gorelli, Alba Aguión, Simon Funge-Smith, Sarah Harper, Dave J. Mills, Gianluigi Nico, Alex Tilley, Stefania Vannuccini, John Virdin, Lena Westlund, Edward H. Allison, Christopher M. Anderson, Andrew Baio, Joshua Cinner, Michael Fabinyi, Christina C. Hicks, Jeppe Kolding, Michael C. Melnychuk, Daniel Ovando, Ana M. Parma, James P. W. Robinson, Shakuntala H. Thilsted   +25 more
openaire   +2 more sources

Small-scale fisheries of San Miguel Bay, Philippines: biology and stock assessment [PDF]

Small scale fisheries, Fishery biology, Fishery resources, Stock assessment, Collected papers, San Miguel Bay, Philippines,
Mines, A.N. (eds.), Pauly, D.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Report on improving smallholder women farmers’ access to finance for small-scale irrigation technologies

, 2023
Widespread use of small power pumps in South Asia has revolutionized agricultural production since the 1970s. In the past few years, solar photovoltaic pumps have become affordable alternatives to diesel and grid-powered electric pumps.
Feed the Future Innovation Lab for Small Scale Irrigation
core   +1 more source

Small-scale Fishery

, 2008
The Locally Based Coastal Resource Management project was implemented since 2002. The overall objectives are to achieve the community-based management for sustainable coastal fishery resources and to alleviate poverty in coastal communities, with ...

core