Results 121 to 130 of about 2,296,289 (312)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Blind Single Channel Deconvolution using Nonstationary Signal Processing

open access: yes, 2003
Blind deconvolution is fundamental in signal processing applications and, in particular, the single channel case remains a challenging and formidable problem. This paper considers single channel blind deconvolution in the case where the degraded observed
Rayner, Peter J. W.   +1 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Modularized Small-Signal Modeling of Grid-Forming Inverters

open access: yesIEEE Access
A wide variety of control schemes for Grid-Forming Inverters (GFMIs) have been developed to enable inverter-based resources (IBRs) to comply with evolving grid-code requirements and deliver essential support services such as frequency and voltage regulation.
Sohail Ahmad Ali   +4 more
openaire   +2 more sources

Small Signal Equivalent Circuit Model and Modulation Properties of Vertical Cavity-Surface Emitting Lasers

open access: yes, 2002
Small signal equivalent circuit model and modulation properties of vertical cavity-surface emitting lasers (VCSEL's) are presented. The modulation properties both in analytic-equation calculation and in circuit model simulation are studied.
Nian Hua   +7 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Stability Analysis and Active Damping Design for Grid-Forming Converters in LC Resonant Grids

open access: yesIEEE Open Journal of the Industrial Electronics Society
In this article, a small-signal model of grid-forming (GFM) converters that takes into account the presence of ac shunt capacitors in the power grid is presented.
SHIYI LIU   +4 more
doaj   +1 more source

A small locally produced windmill for electric power generation as a model for small industry

open access: yes, 1995
A 3-bladed 7 kW windmill has been designed and implemented. This project is serving as a model for the local production of such technology in small industry.
Kamel, Fouad
core   +1 more source

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