Results 91 to 100 of about 1,760,812 (299)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Multilevel small-area estimation of colorectal cancer screening in the United States
Cancer Epidemiology, Biomarkers and Prevention, 2018 Background: The U.S. Preventive Services Task Force recommends routine screening for colorectal cancer for adults ages 50 to 75 years. We generated small-area estimates for being current with colorectal cancer screening to examine sociogeographic ...
Z. Berkowitz +5 more
semanticscholar +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Analyzing regional patterns of mortality data quality and adult mortality for small areas in Brazil, 1980–2010 [PDF]
Demographic ResearchBACKGROUND: Brazil’s profound regional social inequalities raise concerns about their impact on adult mortality and data quality. Although the quality of mortality data has improved in recent decades, substantial regional disparities in death ...
Everton Lima +3 more
doaj +1 more source
Small Area Estimation of Poverty under Structural Change
The Review of Income and Wealth, 2018 Small area poverty maps allow for the design of policies based on spatial differences in welfare. They are typically estimated based on a consumption survey reporting on poverty and a census providing the spatial disaggregation. This paper presents a new
Simon Lange, U. J. Pape, Peter Pütz
semanticscholar +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Small area estimation for semicontinuous data
Biometrical Journal, 2014 Survey data often contain measurements for variables that are semicontinuous in nature, i.e. they either take a single fixed value (we assume this is zero) or they have a continuous, often skewed, distribution on the positive real line. Standard methods for small area estimation (SAE) based on the use of linear mixed models can be inefficient for such ...
Chandra, Hukum, Chambers, Raymond L
openaire +5 more sources
Guidelines to Small Area Estimation for Poverty Mapping
, 2022 Paul Corral +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source