Results 41 to 50 of about 376,666 (267)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of the Formosan Medical AssociationBackground/purpose: Endoscopic remission is presently recognized as the standard therapeutic target in the treatment of ulcerative colitis (UC). However, achieving histological remission is increasingly viewed as a pivotal objective.
Zih-Hao Wei +10 more
doaj +1 more source
Small bowel mesentery fibroma [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2002 Fibromas are rarely localized in the abdomen, but almost always in the mesentery or omentum. We present a 63-year old woman in whom the examination of the upper abdominal pain showed a well distinct abdominal mass at the level of the lower edge of the ...
Čolović Radoje B. +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Scientific ReportsTransarterial radioembolization (TARE) and transarterial chemoembolization (TACE) are recognized locoregional therapies (LRTs) for patients with unresectable hepatocellular carcinoma (uHCC).
Faisal M. Sanai +9 more
doaj +1 more source
Gut and Liver, 2018 Background/AimsWe aimed to evaluate the clinical characteristics and prognosis of Crohn’s disease (CD) in patients who showed proximal small bowel involvement using a nationwide Korean CD cohort.Methods : We reviewed the data from a cohort of patients ...
One Zoong Kim +8 more
doaj +1 more source
Small bowel transplantation [PDF]
BMJ, 1996 Unique problems but now standard treatment for small bowel insufficiency Intestinal transplantation is the logical alternative to definitive parenteral nutrition in patients with chronic intestinal failure after conditions such as necrotising enterocolitis or midgut volvulus. Long term parenteral nutrition is associated with complications such as liver
N, Brousse, O, Goulet
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Clinical Case Reports, 2023 Key Clinical Message Peritoneal encapsulation is most of the time asymptomatic and is found incidentally, but when symptomatic it usually presents with bowel obstruction. CT scan is a gold standard for the diagnosis of bowel encapsulation.
Seyed Hossein Hajimirzaei +6 more
doaj +1 more source