Results 41 to 50 of about 89,945 (259)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
An Unusual Cause of Small Bowel Obstruction in a Child: Ingested Rhubarb
Case Reports in Surgery, 2013 Small bowel obstruction is rarely caused by bezoars concretions formed from undigested foreign material in the gastrointestinal tract. An important cause of bezoars is phytobezoars, formed from vegetables or fruits.
Miguel Glatstein +4 more
doaj +1 more source
A woman with anemia and a small-bowel obstruction [PDF]
Canadian Medical Association Journal, 2004 A previously well 60-year-old woman presented to hospital with a 3-week history of fatigue, anorexia, abdominal pain, nausea and vomiting, and a 4-kg weight loss. She had previously consulted her general practitioner about an episode of diarrhea and dark stools and was found at that time to ...
PIRISI, Mario +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Small bowel volvulus (SBV) in Northcentral Ethiopia
BMC Surgery, 2020 Background Small bowel volvulus (SBV) is a benign gastrointestinal surgical condition in which there is a torsion of all or parts of a segment of small bowel on its mesenteric axis.
Atalel Fentahun Awedew +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Appendiceal knotting causing small bowel strangulation
Journal of Research in Medical Sciences, 2014 Small bowel obstruction is a common cause of an emergency admission in the surgical wards. Acute appendicitis presenting with small bowel obstruction due to appendiceal knotting is a very rare and unsuspected condition in an emergency scenario. We report
Chandan Chatterjee +3 more
doaj
Can small bowel obstruction during pregnancy be treated with conservative management? A review
World Journal of Emergency SurgeryBackground Small bowel obstruction can occur during pregnancy, which, if missed, can lead to dire consequences for both the mother and foetus. Management of this condition usually requires surgical intervention.
Xiao Shuang Ling +3 more
doaj +1 more source
A review of the radiological imaging modalities of non-traumatic small bowel obstruction
South African Family Practice, 2015 Small bowel obstruction is a common clinical presentation that presents a diagnostic conundrum. Over the last 2 decades, there has been a paradigm shift in the radiological investigation of small bowel obstruction (SBO) and in the indication for and ...
Narisha Maharaj, Bhugwan Singh
doaj +1 more source