Results 151 to 160 of about 477,779 (215)

NF-κB activation as a pro-survival signal from pharmacological inhibition of pyruvate dehydrogenase kinase 1 in non-small-cell lung carcinoma cell models. [PDF]

Transl Oncol
Liu Q, Ran M, Shan W, Zhang SL, Tam KY.
europepmc   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

AHCYL1 mediates the tumor-promoting effect of PREX2 in non-small cell lung carcinoma. [PDF]

Theranostics
Lei M, Yeung YT, Nie W, Yang R, Li J, Chen H, Zhao R, Liu K, Dong Z.   +8 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Evaluation of TTF-1, Napsin A, p40, and p63 in the Subtyping of Non-Small Cell Lung Carcinoma: A Cross-Sectional Study from India. [PDF]

Iran J Pathol
Patel S, Anandarama Adiga DS.
europepmc   +1 more source

Performance and considerations in the use of diagnostic mutation panels for clonality testing in non-small-cell lung carcinoma. [PDF]

ESMO Open
Janssen J, Andrade Barbosa B, Machado JC, Hofman P, Kim Y, Ylstra B, Radonic T.   +6 more
europepmc   +1 more source

Common Diseases Presenting in an Uncommon Way: Metastatic Small-Cell Lung Carcinoma Mimicking Merkel Cell Carcinoma. [PDF]

Cureus
Boican A.
europepmc   +1 more source

In Vitro and In Vivo Evaluation of Alectinib-Loaded Dendrimer Nanoparticles as a Drug Delivery System for Non-Small Cell Lung Carcinoma. [PDF]

Pharmaceutics
Atta MR, Atta MR, Al-Ani I, Aldeeb I, AlAzzam KM, Ata T, Almullah MA, Daoud E, Al-Hajji F.   +8 more
europepmc   +1 more source

Small cell lung carcinoma with YAP1 expression and SMARCA4-deficient undifferentiated tumors. [PDF]

Transl Cancer Res
Hayashi T.
europepmc   +1 more source