Results 11 to 20 of about 485,993 (264)

Histopathological transformation to small-cell lung carcinoma in non-small cell lung carcinoma tumors [PDF]

open access: yesTranslational Lung Cancer Research, 2016
Lung cancer is the principal cause of cancer-related death worldwide. The use of targeted therapies, especially tyrosine kinase inhibitors (TKIs), in specific groups of patients has dramatically improved the prognosis of this disease, although inevitably some patients will develop resistance to these drugs during active treatment.
Rita, Dorantes-Heredia   +2 more
openaire   +2 more sources

Iris Metastasis in Small-Cell Lung Carcinoma [PDF]

open access: yesJournal of Thoracic Oncology, 2007
Small-cell lung cancer (SCLC) is characterized by rapid growth and early metastasis. Despite its sensitivity to cytotoxic treatment, until now treatments have failed to control or cure this disease in most patients. Here, we describe a patient with SCLC in which symptoms caused by iris metastasis were the only sign of relapse after multimodality ...
Roenhorst, Anke W. J.   +3 more
openaire   +3 more sources

Rare Combined Small Cell Lung Carcinoma and Lung Squamous Cell Carcinoma Response to PD-1 Inhibitor as Third-Line Therapy: A Case Report

open access: yesCancer Management and Research, 2023
Zhisheng Liu,1,* Junling Zhang,2,* Yunjie Ge,3 Mengli Huang,2 Ye Wang1 1Department of General Surgery, Affiliated Qingdao Hiser Hospital of Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), Qingdao, Shandong People’s Republic
Liu Z, Zhang J, Ge Y, Huang M, Wang Y
doaj  

Neurotensin in human small cell lung carcinoma [PDF]

open access: yesBritish Journal of Cancer, 1984
High levels of neurotensin-like immunoreactivity were found in human small cell lung carcinoma lines. No immunoreactivity was present in non-small cell carcinoma lines and only low amounts in postmortem human lung tissue. The immunoreactive material co-eluted with synthetic neurotensin on two different chromatographic systems.
M, Goedert   +3 more
openaire   +3 more sources

Transformation of Lung Squamous Cell Carcinoma to Small Cell Lung Cancer After Immunotherapy Resistance: A Case Report

open access: yesCancer Management and Research, 2023
Diming Wang,1,* Wei Ye,2,* Dongmei Chen,1 Qingming Shi,1 Dongchun Ma3 1Department of Oncology, Anhui Chest Hospital, Hefei, 230022, People’s Republic of China; 2Department of Pathology, Anhui Chest Hospital, Hefei, 230022, People’s Republic of ...
Wang D, Ye W, Chen D, Shi Q, Ma D
doaj  

Cytokeratin-negative small cell lung carcinoma

open access: yesRare Tumors, 2011
Cytokeratins (CK) are good markers of epithelial tumors, and most of carcinomas including small cell lung carcinoma (SCLC) expresses CK. Herein reported is a case of SCLC without CK expression.
Tadashi Terada
doaj   +1 more source

Characteristics of Peripheral versus Central Lung Cancer Since 2000 [PDF]

open access: yesKosin Medical Journal, 2014
Objectives The aim of this study was to explore the changes of bronchoscopic features according to epidemiologic change of lung cancer. Methods We performed a retrospective review of the clinical characteristics of 1,139 lung cancer patient who underwent
So Young Ock   +6 more
doaj   +1 more source

the Immunohistochemical Study of Stathmin-1 as A Prognostic factor In Non-small cell lung carcinoma

open access: yesمجلة كلية الطب, 2023
Background Stathmin1 (also known as metablastin) is a major microtubule-depolymerizing protein that involved in cell cycle progression and cell motility.
Nadhema Bahaa Hussein Wetwet   +3 more
doaj   +1 more source

Histological transformation of adenocarcinoma to small cell carcinoma lung as a rare mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors: Report of a case with review of literature

open access: yesLung India, 2018
A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment.
Monalisa Hui   +3 more
doaj   +1 more source

Long noncoding nature brain-derived neurotrophic factor antisense is associated with poor prognosis and functional regulation in non–small cell lung caner

open access: yesTumor Biology, 2017
In this study, we evaluated the prognostic potential and functional regulation of human nature antisense, brain-derived neurotrophic factor antisense, in non–small cell lung cancer.
MingJing Shen   +5 more
doaj   +1 more source

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