Results 31 to 40 of about 10,953,879 (308)

Mapping of Multiple DNA Gains and Losses in Primary Small Cell Lung Carcinomas by Comparative Genomic Hybridization [PDF]

, 1994
Comparative genomic hybridization was applied for a comprehensive screening of under- and overrepresentation of genetic material in 13 autoptic small cell lung cancer specimens.
Speicher, Michael R., Cremer, Thomas, Petersen, Iver, Ried, Thomas, Manoir, Stanislas du, Schröck, Evelin, Holtgreve-Grez, Heidi   +6 more
core   +1 more source

EGFR mutation testing in non-small cell lung cancer (NSCLC)

Journal of Infection and Public Health, 2012
Summary: Lung carcinoma is subdivided into small cell carcinoma and non-small cell carcinoma (NSCLC). NSCLC is heterogeneous group of carcinomas and accounts for 70–80% of lung cancer. NSCLC is further divided into adenocarcinoma, squamous cell carcinoma,
Fouad Al Dayel
doaj   +1 more source

Pulmonary pleomorphic carcinoma presenting as undifferentiated non-small cell carcinoma with giant cells: A case report and review of literature

Respiratory Medicine Case Reports, 2020
Pulmonary pleomorphic carcinoma (PPC) is a poorly differentiated non-small cell lung carcinoma, including squamous cell carcinoma, adenocarcinoma, or undifferentiated non-small cell lung carcinoma with at least 10% spindle and/or giant cells.
Jae-Han Jeong, Hong-Joo Seo, Sung-Ho Yoon, Ran Hong   +3 more
doaj   +1 more source

Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. [PDF]

PLoS ONE, 2011
Squamous cell lung carcinomas account for approximately 25% of new lung carcinoma cases and 40,000 deaths per year in the United States. Although there are multiple genomically targeted therapies for lung adenocarcinoma, none has yet been reported in ...
Amit Dutt, Alex H Ramos, Peter S Hammerman, Craig Mermel, Jeonghee Cho, Tanaz Sharifnia, Ajit Chande, Kumiko Elisa Tanaka, Nicolas Stransky, Heidi Greulich, Nathanael S Gray, Matthew Meyerson   +11 more
doaj   +1 more source

MMP-10 is overexpressed, proteolytically active and a potential target for therapeutic intervention in human lung carcinomas [PDF]

, 2004
NoMatrix metalloproteinase (MMP)-mediated degradation of the extracellular matrix is a major factor for tumor development and expansion. This study analysed MMP-10 protein expression and activity in human lung tumors of various grade, stage, and type to ...
Tijani, S., Jason H. Gill, Martin, Sandie W., Alan J. Mearns, Alan Anthoney, Mearns, A.J., Kirwan, I.G, Anikin, V.A., Anikin, V.A, Gill, J.H, Tijani, S, Loadman, Paul, Anthoney, A, Jill M. Seargent, Sandie W. Martin, Mearns, Alan J., Kirwan, Ian G., Seargent, Jill M., Anthoney, Alan, Loadman, P.M, Seargent, J.M, Mearns, A.J, Anikin, Vladimir A., Ian G. Kirwan, Tijani, Sidiq, Bibby, M.C, Martin, S.W, Sidiq Tijani, Bibby, Michael C., Loadman, Paul M., Gill, Jason H., Michael C. Bibby, Paul M. Loadman, Vladimir A. Anikin   +33 more
core   +1 more source

The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma [PDF]

, 2014
The identification of genes responsible for causing cancers from gene expression data has had varied success. Often the genes identified depend on the methods used for detecting expression patterns, or on the ways that the data had been normalized and ...
Ian Bailey, Dalby, A.R., Bailey, I., Andrew Dalby   +3 more
core   +1 more source

Small cell carcinoma of the kidney: a case report and analysis of data from the Surveillance, Epidemiology, and End Results registry

Journal of Medical Case Reports, 2019
Background Primary small cell carcinoma of the kidney is an extremely rare neoplasm. The clinical features of small cell carcinoma of the kidney are not well established due to its rarity and scarcity of case reports.
Charles Chu, Chung-Yuan Hu, Rashmi Batra, Albert Y. Lin   +3 more
doaj   +1 more source

Combined small-cell lung carcinoma

OncoTargets and Therapy, 2018
Currently, studies assessing combined small-cell lung carcinoma (C-SCLC) are relatively scarce and limited. Indeed the clinicopathological features, treatment, and prognosis of patients with C-SCLC have not been fully determined. The incidence of C-SCLC ranges from 5%-28% in different studies, which is related to the specimen types used.
Jing Qin, Hongyang Lu
openaire   +4 more sources

MYC is a metastasis gene for non-small-cell lung cancer. [PDF]

, 2009
Metastasis is a process by which cancer cells learn to form satellite tumors in distant organs and represents the principle cause of death of patients with solid tumors. NSCLC is the most lethal human cancer due to its high rate of metastasis.
Christian Korn, Emanuele Zanucco, Potapenko, Tamara, Korn, C., Zanucco, E., Castro, I., Inês Castro, Fatih Ceteci, Potapenko, T., Ceteci, F., Rapp, Ulf R., Luetkenhaus, Katharina, Ulf R Rapp, Korn, Christian, Tamara Potapenko, Serafin, V., Christiaan Karreman, Castro, Inês, Luetkenhaus, K., Ceteci, Fatih, Zanucco, Emanuele, Valentina Serafin, Karreman, Christiaan, Karreman, C., Serafin, Valentina, Katharina Luetkenhaus, Rapp, U. R.   +26 more
core   +2 more sources

Modulatory effects of T-cadherin on cell behavior and growth factor receptor activity in carcinoma cells [PDF]

, 2014
Cancer is a major health problem. Epidermal growth factor receptor (EGFR) pathway plays an important role in cancer progression. EGFR-targeted anti-cancer drugs are being developed to improve anti-cancer therapy.
Maslova, Kseniya
core   +1 more source