Results 81 to 90 of about 680,918 (208)

Potential novel therapy targets in neuroendocrine carcinomas of the breast [PDF]

open access: yes, 2018
Neuroendocrine carcinoma (NEC) of the breast is a rare, special type of breast cancer, reportedly constituting 2% to 5% of all breast cancers. Although breast NEC does not have a specific targeted therapy, several new targeted therapies based on specific
Contreras, Elma   +7 more
core   +2 more sources

microRNA. Diagnostic Perspective [PDF]

open access: yes, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +2 more sources

Subcuteneous swelling as the first clinical manifestation of small cell carcinoma of lung

open access: yesClinics and Practice, 2012
Subcutaneous swelling as first clinical presentation of small cell lung carcinoma is uncommon and rarely reported in literature. This case highlights a rare presentation in which subcutaneous swelling was the first clinical manifestation of a small cell ...
Sunil Kumar   +3 more
doaj   +1 more source

HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers [PDF]

open access: yes, 2010
The search for novel tumour antigens that are either uniquely expressed or over-expressed in a wide variety of tumours is still ongoing. Because of their expression in a broad spectrum of cancers and limited expression in normal tissues, cancer/testis ...
Badoual, C   +6 more
core  

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. [PDF]

open access: yes, 2017
Activating transcription factor 5 (ATF5) is a cellular prosurvival transcription factor within the basic leucine zipper (bZip) family that is involved in cellular differentiation and promotes cellular adaptation to stress.
Angelastro, James M, Sears, Thomas K
core   +2 more sources

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

open access: yesNature Communications, 2018
Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and ...
Kyren A. Lazarus   +19 more
doaj   +1 more source

Expression and Clinicopathologic Significance of Human Achaete-scute Homolog 1 in Pulmonary Neuroendocrine Tumors

open access: yesChinese Journal of Lung Cancer, 2010
Background and objective Human achaete-scute homolog 1 (hASH1) gene plays a critical role in development of the central nervous system, automatic nervous system, adrenal medullary chromaffin cells, thyroid C cells and pulmonary neuroendocrine cells.
Donghan ZHENG   +6 more
doaj  

Sudden onset acute liver failure in a patient with clinically occult small cell lung carcinoma: autopsy report and review of the medical literature

open access: yesAutopsy and Case Reports, 2019
Liver metastases are commonly found in advanced cancer patients; however, acute liver failure secondary to diffuse liver infiltration is rare. Small cell lung carcinoma accounts for 15% of lung carcinomas.
Massimiliano Guerriero   +4 more
doaj   +1 more source

Determination of safe margin in the surgical pathologic specimens of non-small cell carcinoma of the lung [PDF]

open access: yes
Background and Aim: Local recurrences of the tumor at the surgical margin are serious problems in pulmonary resections for lung cancer. The aim of this study is to determine the involved margins and safe distances of the resection sites from tumor for ...
رحیمی راد, محمدحسین   +6 more
core  

Histological Transformation to Small Cell Carcinoma of an Adenosquamous Carcinoma of the Lung With Epidermal Growth Factor Receptor Mutation in Exons 20 and 21 After Treatment With Erlotinib: Case Report

open access: yesClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2019
Lung carcinoma currently represents 1 of the leading causes of death from cancer worldwide and regionally. The molecular identification of sensitive mutations of targeted treatment have changed the strategies of pharmacologic management in non-small cell
Liliana Fernández-Trujillo   +5 more
doaj   +1 more source

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