Results 231 to 240 of about 2,107,366 (284)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

DFTB Parametrization at the Example of Platinum-Implementation, Validation and Practical Considerations. [PDF]

J Comput Chem
Purtscher FRS, Penz A, Gallmetzer JM, Gamper J, Hofer TS.   +4 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

To shift or not to shift: identifying and correcting patient motion after couch rotations in non-coplanar intracranial radiosurgery with stereoscopic X-ray imaging. [PDF]

J Appl Clin Med Phys
Da Silva Mendes V, Garny S, Huang L, Schönecker S, Trapp C, Fuchs F, Kurz C, Belka C, Landry G, Reiner M, Corradini S.   +10 more
europepmc   +1 more source

Preliminary efficacy of pharmacological treatments on sluggish cognitive tempo (cognitive disengagement syndrome): a systematic review and meta-analysis. [PDF]

Front Psychiatry
Kılınçel Ş, Bulut F, Göksel P, Usta MB, Kılınçel O.   +4 more
europepmc   +1 more source

Evaluation of relative deviations in virtual articulators for simulating occlusal contacts at increased vertical dimensions. [PDF]

J Adv Prosthodont
Biren E, Saygılı S, Bilgen B, Sülün T.   +3 more
europepmc   +1 more source

Can a novice dentist, using a dynamic navigation system, achieve the accuracy of experts using freehand implant placement? a retrospective study. [PDF]

BMC Oral Health
Zheng S, Xia J, Guo B, Chen J, Feng J, Wang L, Ding Y, Yang F.   +7 more
europepmc   +1 more source

VOC Emission Screening of Consumer Products in Microchambers: Comparison of Online PTR-MS and Offline TD-GC-MS Analysis. [PDF]

Anal Chem
Klein L, Haug H, Stenzel A, Beauchamp J, Roloff A.   +4 more
europepmc   +1 more source