Results 101 to 110 of about 10,910,180 (370)
Correction of small bowel function as a new direction for treating patients with metabolic syndrome [PDF]
Aim. To provide a rationale for and to evaluate the therapeutic efficiency of the combined use of pancreatic enzymes and actovegin in the combination therapy of patients with metabolic syndrome (MS) on the basis of comprehensive clinical and functional ...
Ya M Vakhrushev, M V Lyapina
doaj +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
A counterexample to 'Algebraic function fields with small class number' [PDF]
I give a counter example of function field over GF(2) of genus 4 with class number one.
Stirpe, Claudio
core
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Stability of a characterization of normal distributions based on the first two conditional moments
A characterization of normal distributions of two independent random variables X and Y with a finite E[X2] based on the linearity of E[X|X+Y] and the homoscedasticity of var[X|X+Y] given by Rao (1976) is proved to be stable.
Truc T. Nguyen, Khoan T. Dinh
doaj +1 more source
Small values of the Euler function and the Riemann hypothesis
Let $\vfi$ be Euler's function, $\ga$ be Euler's constant and $N_k$ be the product of the first $k$ primes. In this article, we consider the function $c(n) =(n/\vfi(n)-e^\ga\log\log n)\sqrt{\log n}$. Under Riemann's hypothesis, it is proved that $c(N_k)$
Nicolas, Jean-Louis
core +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Derivatives of Meromorphic Functions with Multiple Zeros and Small Functions
Letfzbe a meromorphic function inℂ, and letαz=Rzhz≢0, wherehzis a nonconstant elliptic function andRzis a rational function. Suppose that all zeros offzare multiple except finitely many andTr,α=oTr,fasr→∞. Thenf'z=αzhas infinitely many solutions.
Pai Yang, Peiyan Niu
openaire +4 more sources