Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Small molecule-mediated refolding and activation of myosin motor function
eLife, 2014 The small molecule EMD 57033 has been shown to stimulate the actomyosin ATPase activity and contractility of myofilaments. Here, we show that EMD 57033 binds to an allosteric pocket in the myosin motor domain.
Michael B Radke +5 more
doaj +1 more source
Small x nonlinear evolution with impact parameter and the structure function data
, 2011 The nonlinear Balitsky-Kovchegov equation at small x is solved numerically, incorporating impact parameter dependence. Confinement is modeled by including effective gluon mass in the dipole evolution kernel, which regulates the splitting of dipoles with ...
Anna M. Staśto +7 more
core +1 more source
Smooth backfitting for additive modeling with small errors-in-variables, with an application to additive functional regression for multiple predictor functions [PDF]
, 2017 Kyunghee Han +2 more
openalex +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Small-diameter portacaval h-graft shunt: A paradigm shift back to surgical shunting in the management of variceal bleeding in patients with preserved liver function [PDF]
, 2000 Donald J. Hillebrand +5 more
openalex +1 more source
Artin L-functions of small conductor
Research in Number Theory, 2017 We study the problem of finding the Artin L-functions with the smallest conductor for a given Galois type. We adapt standard analytic techniques to our novel situation of fixed Galois type and get much improved lower bounds on the smallest conductor.
John W. Jones, David P. Roberts
openaire +4 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Relation between differential polynomials and small functions [PDF]
, 2010 Benharrat Belaϊdi, Abdallah El Farissi
openalex +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source