Results 191 to 200 of about 5,657,410 (310)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Tick-small mammal relationships in urban and forest environments in Yamagata Prefecture, Japan: First confirmation of the establishment of southern tick species in northern Japan. [PDF]

Int J Parasitol Parasites Wildl
Komine H, Ishikawa S.
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Metagenomic analysis of commensal small mammal samples from an international cargo shipping area, Bangkok Port, reveals potential zoonotic pathogens and implications for One Health surveillance. [PDF]

One Health
Sirimongkol D, Wongluechai P, Chamsai T, Weluwanarak T, Chaipromkhieo N, Sangkachai N, Tonchiangsai K, Pabutta C, Kerdsiri P, Sariya L.   +9 more
europepmc   +1 more source

CNTN2 Deficiency Disrupts Ascending Auditory Neuroglial Interactions and Redox Homeostasis in Neural Presbycusis

Advanced Science, EarlyView.
. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Penghui Chen, Jingyi Zhu, Sihan Huang, Beibei Xu, Maoli Duan, Jingrong Lv, Jiarui Chen, Jun Yang, Shule Hou   +8 more
wiley   +1 more source

Correction to "Assessment of Nontarget Small Mammal Occupancy Using Broadly Designed Camera Arrays". [PDF]

Ecol Evol
europepmc   +1 more source

<i>Leptospira</i> prevalence and lineages vary across land-use types due to shifts in small mammal communities. [PDF]

Appl Environ Microbiol
Rajaonarivelo JA, Kauffman KM, Randriamoria TM, Herrera JP, Wickenkamp N, Turpin M, Baudino F, Young HS, Soarimalala V, Goodman SM, Nunn CL, Tortosa P.   +11 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Prevalence of zoonotic nematode <i>Calodium hepaticum</i> varies with small mammal community diversity across a heterogenous landscape in Eastern Uganda. [PDF]

Parasitology
Johnson E, Ajambo D, Capstick M, Arinaitwe M, Ericsson O, Besigye F, Raghwani J, Dennis TPW, Bogere R, Nankasi A, Atuhaire A, Rowell C, Namukuta A, Mohamed A, Adriko M, Lamberton P, Tukahebwa E, Allan KJ, Faust C.   +18 more
europepmc   +1 more source

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

Advanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li, Kelly Yichen Li, Chiara Nicoletti, Stephen Kwok‐Wing Tsui, Pier Lorenzo Puri, Qin Cao, Kevin Y. Yip   +6 more
wiley   +1 more source