Results 71 to 80 of about 5,657,410 (310)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Background European hedgehogs (Erinaceus europaeus) are frequently infected with a variety of endoparasites. The hedgehogs’ synanthropic lifestyle results in frequent contact with pets and humans, posing the risk of parasite spillover from a One Health ...
Karolin Schütte +6 more
doaj +1 more source
We investigated the relations between environmental features (biotic and abiotic) and small mammal communities in the Groendal Wilderness Area, South Africa. Habitat architecture (expressed as both horizontal and vertical foliage density) and total plant
L.M. Els, G.I.H. Kerley
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Many aspects of Hystricidae porcupine ecology in South Asia, including that of the Malayan porcupine (Hystrix brachyura), remain poorly studied. Part of this species’ global range falls within Bangladesh, where the presence and distribution of porcupines
Muntasir Akash +5 more
doaj +1 more source
Inside and outside of small mammal exclusion fence on SGS experimental ...
Milchunas, Daniel, photographer
core
Road Zone Effects in Small-Mammal Communities
Our study focused on the putative effects of roads on small-mammal communities in a high desert region of southern Utah. Specifically, we tested whether or not roads create adjacent zones characterized by lower small- mammal densities, abundance, and ...
J A Bissonette +5 more
core +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Myiasis in European hedgehogs (Erinaceus europaeus)
Myiasis due to parasitic fly larvae (maggots) can have major consequences for animal health and welfare. The European hedgehog Erinaceus europaeus is frequently presented in rehabilitation centres and veterinary practices due to health problems ...
Karolin Schütte +5 more
doaj +1 more source

