Results 141 to 150 of about 390,519 (313)

Are day-active small mammals rare and small birds abundant in Australian desert environments because small mammals are inferior thermoregulators?

open access: yes, 2004
Small desert birds are typically diurnal and highly mobile (hence conspicuous) whereas small non-volant mammals are generally nocturnal and less mobile (hence inconspicuous). Birds are more mobile than terrestrial mammals on a local and geographic scale,
C Cooper (7714754)   +2 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Small mammals from Sima de los Huesos

open access: yes, 1997
A small collection of rodents from Sima de los Huesos helps to clarify the stratigraphic position of this famous human locality. The presence of Allocricetus bursae and Pliomys lenki relictus and the size of A.
Laplana Conesa, C.   +3 more
core   +1 more source

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

open access: yesAdvanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell   +7 more
wiley   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

Miocene rodent evolution and migration. Muroidea from Pakistan, Turkey and Northern Africa. Geologica Ultraiectina (307)

open access: yes, 2009
Detailed research on fossil rodents from Pakistan, Turkey, northern Africa and Europe provides a better understanding of the evolutionary history of the Muroidea, especially of the Murinae, Myocricetodontinae and Rhizomyinae.
Wessels, W.   +3 more
core  

Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

Roads and wildlife: a study of the effects of roads on mammals in roadside habitats [PDF]

open access: yes, 2003
There is increasing concern about the adverse effects of the road network on wildlife. The impacts of roads in the ecological landscape include habitat loss, habitat fragmentation and habitat degradation.
Underhill, Jackie E   +1 more
core  

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

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