Results 161 to 170 of about 10,015,764 (349)
Analyses of electronic wave functions and chemical binding in small molecules
, 1966 C. Edmiston
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Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Increased uptake of biologics in historically small molecule blockbuster-dominated therapeutic areas
, 1969 Duncan A N Emerton, Mark J. Belsey
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Early changes in blood brain barrier permeability to small molecules after transient cerebral ischemia. [PDF]
, 1984 J. I. Sage +2 more
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
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Changes of vibrational lifetimes with minor structural modification of small polyatomic molecules [PDF]
, 1982 C. Kolmeder, Wolfgang Zinth, W. Kaiser
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Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
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Tritium Labeling of Neuromedin S by Conjugation with [3H]N‑Succinimidyl Propionate
ACS Omega, 2023 Martin R. Edelmann +3 more
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