Results 181 to 190 of about 10,015,764 (349)

The use of maximum entropy in thea prioriphasing of small molecules [PDF]

, 1987
G. Bricogne, C. J. Gilmore
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Cardiotoxicity of small-molecule kinase inhibitors in cancer therapy. [PDF]

Exp Hematol Oncol
Zhu S, Fu K, Li S, Yang C, Pan C, Wang X, Wang F, Yu X, To KKW, Fu L.   +9 more
europepmc   +1 more source

IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2. [PDF]

, 1994
R M Stack, Deborah J. Lenschow, G S Gray, Jeffrey A. Bluestone, Frank W. Fitch   +4 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Cost-Effective and Scalable Synthesis of 4-Bromo-1,2-dimethyl-1H-imidazole: A Key Building Block for Bioactive Molecules

SynOpen, 2023
Muthalagu Vetrichelvan, Veeranjaneyulu Lanke, Bellam Chandu, Arvind Mathur, Anuradha Gupta   +4 more
doaj   +1 more source

Matrix isolation studies of small molecules

, 1971
J. Pacansky
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

PP 5.5 – 00026 Targeting Tat/TAR interactions with the superelongation complex for the development of novel treatments for HIV/AIDS

Journal of Virus Eradication, 2022
U. Schulze-Gahmen, T. Divita, P. Kandel, M. Arkin, M. Ott   +4 more
doaj  

A Small-Molecule Drug for the Self-Checking of Mitophagy. [PDF]

Angew Chem Int Ed Engl
Gao Y, Bai Q, Ren Y, Shao X, Zhang M, Wu L, Lewis SE, James TD, Chen X, Chen Q.   +9 more
europepmc   +1 more source