Results 191 to 200 of about 2,196,436 (350)
Predictive Toxicology Approaches for Small Molecule Oncology Drugs [PDF]
, 2010 Timothy J. Maziasz +4 more
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Small-molecule degron mimetics for targeted protein degradation. [PDF]
Essays BiochemLiu X.
europepmc +1 more source
MOESM2 of BCL::Conf: small molecule conformational sampling using a knowledge based rotamer library
, 2015 Sandeepkumar Kothiwale +2 more
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Embelin, a small molecule quinone with a co-clinical power for castrate-resistant prostate cancer [PDF]
, 2014 Radhika Poojari
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Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Optimizing Stability in Dynamic Small-Molecule Binding Proteins. [PDF]
J Am Chem SocScherer M +3 more
europepmc +1 more source
Targeting receptors and DNA secondary structures with small molecules and calix[4]arene conjugates [PDF]
, 2016 Qiran Sheng
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Characterizing diffusion‐controlled release of small‐molecules using quantitative MRI in view of applications to orthopedic infection [PDF]
Greg Hong +6 more
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