Results 221 to 230 of about 10,015,764 (349)

Elimination of Neuroblastoma and Small-Cell Lung Cancer Cells With an Anti-Neural Cell Adhesion Molecule Immunotoxin [PDF]

, 1996
Denis‐Claude Roy, Sophie Ouellet, Caroline Houillier, P D Ariniello, Claude Perreault, John M. Lambert   +5 more
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

HSF1 Activation Mechanisms, Disease Roles, and Small Molecule Therapeutics. [PDF]

Int J Biol Sci
Zhang B, Fan Y, Tan K.
europepmc   +1 more source

Accurate density functional calculations on frequency-dependent hyperpolarizabilities of small molecules [PDF]

, 1998
S. J. A. van Gisbergen, J. G. Snijders, Evert Jan Baerends   +2 more
openalex   +1 more source

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Cancer Cell, 2019
Yue Huang, R. Su, Yue Sheng, Lei Dong, Ze Dong, Hongjiao Xu, Tengfeng Ni, Zijie Zhang, Tao Zhang, Chenying Li, Li Han, Zhenyun Zhu, F. Lian, Jiangbo W, Qiang-qiang Deng, Yungui Wang, M. Wunderlich, Zhi-wei Gao, Guoyu Pan, D. Zhong, Hu Zhou, Naixia Zhang, J. Gan, Hualiang Jiang, J. Mulloy, Zhijian Qian, Jianjun Chen, Cai-Guang Yang   +27 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Small-Molecule Tyrosinase Inhibitors for Treatment of Hyperpigmentation. [PDF]

Molecules
Ni X, Luo X, Jiang X, Chen W, Bai R.
europepmc   +1 more source

Synthesis and screening of small molecule libraries active in binding to DNA [PDF]

, 1997
Gerald W. Shipps, Kent E. Pryor, Jun Xian, David Skyler, Eric H. Davidson, Julius Rebek   +5 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The evolution and application of RNA-focused small molecule libraries. [PDF]

RSC Chem Biol
Taghavi A, Springer NA, Zanon PRA, Li Y, Li C, Childs-Disney JL, Disney MD.   +6 more
europepmc   +1 more source