Results 291 to 300 of about 10,015,764 (349)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

TLK1 as a therapeutic target in TMZ resistant glioblastoma using small molecule inhibitor. [PDF]

Sci Rep
Priya B, Kirubakaran S.
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Precision Medicine for Pediatric Glioma and NF1-Associated Tumors: The Role of Small Molecule Inhibitors. [PDF]

Curr Oncol
Renzi S, Bennett J, Thacker N, Cacciotti C.   +3 more
europepmc   +1 more source

Efficacy and safety of small molecule drugs in the treatment of pityriasis rubra pilaris-A systematic review. [PDF]

Front Med (Lausanne)
Zhang X, Wei K, Song H, Chen X, Yang J, Zhao J, Jiang Y, He X.   +7 more
europepmc   +1 more source

KinasePred: A Computational Tool for Small-Molecule Kinase Target Prediction. [PDF]

Int J Mol Sci
Di Stefano M, Piazza L, Poles C, Galati S, Granchi C, Giordano A, Campisi L, Macchia M, Poli G, Tuccinardi T.   +9 more
europepmc   +1 more source

Redox-active inverse crowns for small molecule activation. [PDF]

Nat Chem
Maurer J, Klerner L, Mai J, Stecher H, Thum S, Morasch M, Langer J, Harder S.   +7 more
europepmc   +1 more source

Discovery of a Small Molecule with an Inhibitory Role for RAB11. [PDF]

Int J Mol Sci
Lempicki C, Milosavljevic J, Laggner C, Tealdi S, Meyer C, Walz G, Lang K, Campa CC, Hermle T.   +8 more
europepmc   +1 more source