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Small-molecule ambipolar transistors
Physical Chemistry Chemical Physics, 2022Small-molecule materials showing ambipolar transistor properties are reviewed.
Toshiki Higashino, Takehiko Mori
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Small molecules and small molecule drugs in regenerative medicine
Drug Discovery Today, 2014Regenerative medicine is an emerging, multidisciplinary science that aims to replace or regenerate human cells, tissues or organs, to restore or establish normal function. Research on small molecules and small molecule drugs in regenerative medicine is currently increasing.
Baisong, Lu, Anthony, Atala
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Current Medicinal Chemistry, 2021
Pain is a symptom of ninety percent of human diseases, and pain management is a very important medicinal problem. Various modulators of the pain response have been detected, and analgesic effects are obtained by increasing inhibition or decreasing excitation in the nervous system.
Sergey S. Laev, Nariman F. Salakhutdinov
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Pain is a symptom of ninety percent of human diseases, and pain management is a very important medicinal problem. Various modulators of the pain response have been detected, and analgesic effects are obtained by increasing inhibition or decreasing excitation in the nervous system.
Sergey S. Laev, Nariman F. Salakhutdinov
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Chemical Communications, 2009
A PEG based 3D hydrogel slide was developed specifically for small-molecule microarraying purposes, which displayed improved loading capacity, signal sensitivity and spot morphology compared with a commercially available slide and comparative 2D slide.
David M, Marsden +3 more
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A PEG based 3D hydrogel slide was developed specifically for small-molecule microarraying purposes, which displayed improved loading capacity, signal sensitivity and spot morphology compared with a commercially available slide and comparative 2D slide.
David M, Marsden +3 more
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Small molecules as geneticists
Nature Methods, 2006Stuart Schreiber and colleagues show how small molecule sensitivities can be used to probe the natural genetic variation present in populations of organisms.
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The Journal of Physical Chemistry A, 2016
Quantum mechanics builds large-scale graphs (networks): the vertices are the discrete energy levels the quantum system possesses, and the edges are the (quantum-mechanically allowed) transitions. Parts of the complete quantum mechanical networks can be probed experimentally via high-resolution, energy-resolved spectroscopic techniques.
Attila G, Császár +2 more
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Quantum mechanics builds large-scale graphs (networks): the vertices are the discrete energy levels the quantum system possesses, and the edges are the (quantum-mechanically allowed) transitions. Parts of the complete quantum mechanical networks can be probed experimentally via high-resolution, energy-resolved spectroscopic techniques.
Attila G, Császár +2 more
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Complexity from small molecules
Nature Nanotechnology, 2018Chemical oscillations emerge during the chemically fuelled self-assembly of a perylene diimide derivative as a result of simple feedback mechanisms.
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Small Molecule Shape-Fingerprints
Journal of Chemical Information and Modeling, 2005The optimal overlap between two molecular structures is a useful measure of shape similarity. However, it usually requires significant computation. This work describes the design of shape-fingerprints: binary bit strings that encode molecular shape. Standard measures of similarity between two shape-fingerprints are shown to be an excellent surrogate ...
James A, Haigh +3 more
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