Results 121 to 130 of about 7,708,764 (303)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Small-object detection and its applications
Small-object detection is a crucial task in computer vision with numerous applications ranging from medical imaging to autonomous driving. This report explores the efficacy of YOLOv8.1, a state-of-the-art single-stage object detector, specifically ...
Ho, Yong Xian
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Poster shows an image of a vest worn by volunteers who watch over young protesters during demonstrations and clashes. The phrase "We are all yellow object" printed inside a small square at the center of the poster refers to Hong Kong Police calling a ...
core
Attention modules in convolutional neural networks for small object recognition
A problem of small object recognition is frequently encountered in biomedical and security systems. However, the detection of such objects is often complicated by presence of dense clouds or infrastructure objects.
D.I. Krasnov
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
YOLO-LIO: A Real-Time Enhanced Detection and Integrated Traffic Monitoring System for Road Vehicles
Traffic violations and road accidents remain significant challenges in developing safe and efficient transportation systems. Despite technological advancements, improving vehicle detection accuracy and enabling real-time traffic management remain ...
Rachmat Muwardi +7 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Masked strategies for images with small objects
The hematology analytics used for detection and classification of small blood components is a significant challenge. In particular, when objects exists as small pixel-sized entities in a large context of similar objects. Deep learning approaches using supervised models with pre-trained weights, such as residual networks and vision transformers have ...
Martin Gillis +4 more
openaire +3 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Do small group health insurance regulations influence small business size? [PDF]
The cost of health insurance has been the primary concern of small business owners for several decades. State small group health insurance reforms, implemented in the 1990s, aimed to control the variability of health insurance premiums and to improve ...
Fulton, Brent +3 more
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