Results 121 to 130 of about 4,398,040 (341)
A Novel Score Combining Magnetic Resonance Spectroscopy Parameters and Systemic Immune-inflammation Index Improves Prognosis Prediction in Non-small-cell Lung Cancer With Brain Metastases [PDF]
, 2021 Dong Guo +7 more
openalex +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The critical layer during transition of the spiral Poiseuille flow in an annular gap
, 2017 Subject of this paper falls under the broad heading of the propagation of disturbances causing transition in a fully developed spiral annular flow. The problem is approached through reformulation of the linearised equations of motion governing small ...
Ram, Venkatesa I. Vasanta
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Elliptic problems with small parameter [PDF]
, 2014 In this thesis we consider diverse aspects of existence and correctness of asymptotic solutions to elliptic differential and pseudodifferential equations. We begin our studies with the case of a general elliptic boundary value problem in partial derivatives.
openaire
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Қарағанды университетінің хабаршысы. Математика сериясыThe article is devoted to the study of a singularly perturbed initial problem for a linear differential equation with a piecewise constant argument second-order for a small parameter.
A.E. Mirzakulova, K.T. Konisbayeva
doaj +1 more source
Corrigendum to “On a Nonlinear Wave Equation Associated with Dirichlet Conditions: Solvability and Asymptotic Expansion of Solutions in Many Small Parameters” [PDF]
, 2017 Le Thi Phuong Ngoc +3 more
openalex +1 more source