Results 161 to 170 of about 4,398,040 (341)

Physicochemical and Structural Parameters Contributing to the Antibacterial Activity and Efflux Susceptibility of Small-Molecule Inhibitors of Escherichia coli

, 2021
Sara S. El Zahed, Shawn French, Maya A. Farha, Garima Kumar, Eric D. Brown   +4 more
openalex   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

ACTION OF DONORS OF HYDROGEN SULFIDE ON THE PARAMETERS OF OXIDATIVE STRESS IN SMALL INTESTINAL MUCOSA OF RATS UNDER CONDITIONS OF THE ENALAPRIL ACTION

, 2018
Yu. O. Sklyarova, Iryna Fomenko
openalex   +1 more source

Effect of tumor and normal lung volumes on the lung volume–dose parameters of IMRT in non–small-cell lung cancer

, 2021
Xi Zou, Linzhen Lan, Lijing Zheng, Jinmei Chen, Feibao Guo, Chuanshu Cai, Jinsheng Hong, Weijian Zhang   +7 more
openalex   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Uncertainty Characterization of Cross-Correlated Random Fields of Thermal Parameters for Small Samples of Frozen Soil

Jiazeng Cao, Tao Wang, Yonglin Feng, Jin Wu, Zhiyang Wang, Guoqing Zhou, Weifeng Wan   +6 more
openalex   +1 more source

On the maximum of discretely sampled fractional Brownian motion with\n small Hurst parameter [PDF]

, 2018
Konstantin Borovkov, Mikhail Zhitlukhin
openalex   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Classical and Bayesian Inference for the Two-Parameter Rayleigh Distribution with Random Censored Data. [PDF]

Entropy (Basel)
Zhang L, Gui W, Zhao Z, Liu M.
europepmc   +1 more source